Best Argireline Face Serums of 2026

Charlotte Powell Avatar
Charlotte Powell
Last Updated: 2 Feb 2026

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Argireline Face Serums are a range of skincare products designed to reduce the appearance of fine lines and wrinkles. These serums contain a peptide called Argireline, which is known for its ability to reduce muscle tension and smooth out the skin. The serums come in various formulations, each with different concentrations of Argireline and other active ingredients. With regular use, these serums can help to improve the overall texture and tone of the skin, leaving it looking plumper and more youthful.

At a Glance: Our Top Picks

HORACE Bio-Retinol Face Serum for Men Cover #TOP 1
HORACE Bio-Retinol Face Serum for Men
ftb score rating icon 9.8
Cos De BAHA Peptide Serum for Youthful Skin Cover #TOP 2
Cos De BAHA Peptide Serum for Youthful Skin
ftb score rating icon 9.7
20% Argireline Serum with Matrixyl and HA Cover #TOP 3
20% Argireline Serum with Matrixyl and HA
ftb score rating icon 9.5

Top 6 Argireline Face Serums

HORACE Bio-Retinol Face Serum for Men

HORACE
3701154702280
30 ml (Pack of 1)
HORACE Bio-Retinol Face Serum for Men Cover
HORACE Bio-Retinol + Argireline Peptide Face Serum for Men - For Wrinkles, Dark Spots and Elasticity - Vegan Skin Care for All Skin Types - Unscented, 30ml

The HORACE Face Serum is designed specifically for men, featuring 98.9% naturally-derived ingredients that help reduce fine lines, wrinkles, and sagging skin, promoting a more youthful look in just eight weeks. This advanced anti-ageing formula combines Bio-Retinol and Argireline Peptide to visibly diminish dark spots while brightening and evening out your skin tone. With its plant-based collagen, it enhances firmness and elasticity, giving your skin a smoother, more radiant appearance. Being unscented and vegan, it suits all skin types, making your daily skincare routine simple and effective.

What We Like
Reduces fine lines and wrinkles
Brightens and evens skin tone
Enhances skin firmness and elasticity
Unscented and suitable for all skin types
Easy to apply daily
#TOP 2

Cos De BAHA Peptide Serum for Youthful Skin

30 ml (Pack of 1)
Cos De BAHA Peptide Serum for Youthful Skin Cover
Cos De BAHA Peptide Serum 30ml w Matrixyl 3000 & Argireline - Korean Skin Care for Anti Wrinkles

The Cos De BAHA Peptide Serum is designed to rejuvenate your skin with its powerful ingredients. It contains niacinamide and hyaluronic acid, which help to smooth away wrinkles and enhance elasticity, giving you a youthful glow. The potent Matrixyl 3000 encourages collagen production, promoting firmer skin. Additionally, Argireline works to relax facial muscles, preventing new lines from forming. With this nutrient-rich serum, your skin can feel vibrant, hydrated, and healthy, making it an essential addition to your skincare routine.

What We Like
Reduces wrinkles and fine lines
Boosts collagen production
Hydrates and plumps skin
Fragrance-free and non-greasy
Easy absorption with hyaluronic acid
#TOP 3

20% Argireline Serum with Matrixyl and HA

B07FDN2FV6
30 ml (Pack of 1)
20% Argireline Serum with Matrixyl and HA Cover
20% Argireline Serum with Matrixyl 3000 and HA

The Argireline Serum by SKIN DEVA is designed to reduce wrinkles in just a few applications. With daily use, you can expect remarkable and visible results. The hyaluronic acid in the formula helps penetrate the skin deeply, enhancing the serum's wrinkle-reducing properties. By incorporating Matrixyl 3000 and argireline, this serum boosts collagen production, promoting smooth and youthful skin. Additionally, it stimulates collagen and elastin synthesis, effectively addressing issues like crow's feet and skin tightness.

What We Like
Reduces wrinkles quickly
Deep skin penetration
Boosts collagen production
Non-greasy and hydrating
#TOP 4

ASTERWOOD MATRIXYL 3000 + ARGIRELINE Serum

ASTERWOOD
Matrixyl 3000 + Argireline Serum 1 oz
ASTERWOOD MATRIXYL 3000 + ARGIRELINE Serum Cover
MATRIXYL 3000 + ARGIRELINE Peptide 1 oz Serum + Organic Hyaluronic Acid - Wrinkle/Aging Fighting - Powerful Line Remover Collagen Booster ASTERWOOD NATURALS Liquid Face Lift in a Bottle

The ASTERWOOD Anti-Aging Serum is designed to rejuvenate your skin, offering hydration and protection for a youthful appearance. It prevents wrinkles and collagen loss by deeply moisturising your skin, improving texture and reducing fine lines. With hyaluronic acid, it stimulates collagen production while locking in moisture, effectively repairing damage. Safe for all skin types, this serum uses pure, well-balanced ingredients, making it a gentle addition to your nighttime skincare routine.

What We Like
Strengthens skin's defence
Prevents wrinkles effectively
Repairs skin damage
Safe for all skin types
No harmful ingredients
#TOP 5

MooGoo Amplified Anti-Ageing Serum with Argireline

25 ml (Pack of 1)
MooGoo Amplified Anti-Ageing Serum with Argireline Cover
MooGoo Amplified Anti-Ageing Serum with Argireline® Amplified Peptide - 50x More Potent Than Regular Argireline® Peptide, 25ml / 0.85 fl.oz.

The MooGoo Anti-Ageing Serum is designed with an advanced formula featuring Modified Acetyl Hexapeptide-8, which is significantly more potent than regular Argireline Peptide. This serum effectively targets fine lines and wrinkles, ensuring deeper penetration into the skin for noticeable results. Additionally, it enhances overall skin quality by improving roughness, radiance, firmness, and elasticity. With the inclusion of BeauActive, it also addresses sun damage and stimulates collagen production, making it a comprehensive solution for those seeking to combat the signs of ageing.

What We Like
Advanced anti-ageing formula
Targets fine lines effectively
Improves skin quality
Stimulates collagen production
Enhances radiance and firmness
#TOP 6

BIOCORE LABS 3-in-1 Snail Mucin Serum

BIOCORE LABS
100 ml (Pack of 1)
BIOCORE LABS 3-in-1 Snail Mucin Serum Cover
Advanced 3 IN 1 SUPER SERUM infused with FACELIFT Argireline Peptide by BIOCORE LABS™ Anti Aging,Moisturizing,Firming Snail Mucin Serum for Face 100ml

The BIOCORE LABS Super Serum combines three powerful ingredients in one easy-to-use bottle, saving you time and money. It contains 80% snail secretion filtrate, which deeply hydrates and refreshes your skin while reducing dullness, all sourced ethically without harming snails. The serum also features 4% Acetyl Hexapeptide-8, known as "Botox in a Bottle," to improve skin elasticity and firmness, giving you a lifted look. Additionally, 2% hyaluronic acid provides instant plumping hydration, perfect for dry or dehydrated skin, helping to keep your skin moisturised and revitalised.

What We Like
Three powerful ingredients combined
High 80% snail mucin content
Boosts skin elasticity and firmness
Instant hydration and plumping
Cruelty-free and skin-safe
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What does Argireline do for your face?

Argireline prevents formation of skin lines and wrinkles in a very similar way to the botulinum toxin (Botox), inhibiting neurotransmitter release at the neuromuscular junction. Argireline does not require under skin muscle injections and it is believed to be relatively safe.

2. Is Argireline good for your skin?

Argireline is also said to be able to optimize the function of collagen, which can not only help to smooth out the skin but also keep it moisturized. In general, Argireline is best when used for anti-aging concerns. It isn't quite as beneficial for younger, healthier skin, but it is still safe to use.

3. Is Argireline like Botox?

Similar to Botox, Argireline works by inhibiting your nerves' ability to release a signal to your muscles, therefore limiting the movements that lead to wrinkles, said Dr. Joshua Zeichner, director of cosmetic & clinical research in dermatology at Mount Sinai Hospital in New York City.

4. Can Argireline cause wrinkles?

Argireline, the brand name for acetyl hexapeptide-3 and acetyl hexapeptide-8, is essentially the closest thing to Botox without the needle, according to Today. Because repeated movements cause the formation of wrinkles, this ingredient blocks your nerves from sending the signals that tell your muscles to move. Dr.

Editor's Notes

During our argireline face serum research, we found 28 argireline face serum products and shortlisted 6 quality products. We collected and analyzed 25,547 customer reviews through our big data system to write the argireline face serums list. We found that most customers choose argireline face serums with an average price of £25.86.

The argireline face serums are available for purchase. We have researched hundreds of brands and picked the top brands of argireline face serums, including HORACE, Cos De BAHA, SKIN DEVA, ASTERWOOD, MooGoo.

Written by
Charlotte Powell Avatar

Charlotte Powell is a dermatologist and a licensed cosmetologist from Westminster, London. However, she was first a cosmetologist from London Beauty Training School. According to Charlotte, she needed better insight into the human skin, hence the dermatology degree. Long before she acquired her degree, she wrote and edited articles, eBooks, and editorials for companies and websites. Charlotte combines her skill and knowledge in providing DIY Beauty tips amongst other fashion related topics.