Best Gluten-Free Digestive Enzyme Supplements of 2025

Phoebe Cooper Avatar
Phoebe Cooper
Last Updated: 2 Feb 2025

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If you struggle with gluten intolerance or digestive issues, you may benefit from trying gluten-free digestive enzyme supplements. These supplements are designed to help break down food more efficiently, making it easier for your body to absorb the nutrients it needs. They often contain a blend of enzymes such as protease, amylase, and lipase, which aid in the digestion of protein, carbohydrates, and fats. While these supplements are not a cure for gluten intolerance or digestive issues, they can provide relief and improve overall digestive health.

At a Glance: Our Top Picks

Solgar Vegan Digestive Enzymes for Digestion Support Cover #TOP 1
Solgar Vegan Digestive Enzymes for Digestion Support
ftb score rating icon 9.9
Enzymedica Digest Complete Vegan Capsules Cover #TOP 2
Enzymedica Digest Complete Vegan Capsules
ftb score rating icon 9.8
NaturesPlus ActiZyme Digestive Enzymes with Probiotics Cover #TOP 3
NaturesPlus ActiZyme Digestive Enzymes with Probiotics
ftb score rating icon 9.6

Top 10 Gluten-Free Digestive Enzyme Supplements

Solgar Vegan Digestive Enzymes for Digestion Support

E2800
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Solgar Vegan Digestive Enzymes for Digestion Support Cover
Solgar Vegan Digestive Enzymes Tablets - Pack of 50 - Lactose Free - Digestion Support - Vegan & Gluten-Free

Solgar Digestive Enzymes are designed to support your digestive system and enhance nutrient absorption. This unique formula features a blend of vegan enzymes, ensuring that you can break down food effectively, even if your diet is healthy. By using these tablets, you can improve your digestion and ensure that essential nutrients are absorbed efficiently. Crafted in small batches, the product prioritises consistency and purity, making it a natural choice for wellness enthusiasts.

What We Like
Supports nutrient absorption
Vegan and gluten-free
Unique enzyme formula
Crafted in small batches
100% recyclable packaging
#TOP 2

Enzymedica Digest Complete Vegan Capsules

31055
Enzymedica Digest Complete Vegan Capsules Cover
Enzymedica, Digest Complete, Digestive Enzymes, 30 Vegan Capsules, High-dose, Vegetarian, Soy-Free, Gluten-Free, Non-GMO

Enzymedica Digest Complete offers a powerful enzyme-rich formula that assists in breaking down proteins, fats, and carbohydrates. This makes digestion easier for you, ensuring your body absorbs nutrients more effectively. The product features plant-based extracts that have traditionally supported digestive health, providing additional benefits. Being vegan and gluten-free, you can enjoy these capsules without worrying about artificial additives. Conveniently packaged in easy-to-take capsules, this supplement is perfect for your busy lifestyle.

What We Like
Enzyme-rich formula
Plant-based extracts
Vegan and gluten-free
Convenient capsule form
High-quality standards
#TOP 3

NaturesPlus ActiZyme Digestive Enzymes with Probiotics

NaturesPlus ActiZyme Digestive Enzymes with Probiotics Cover
NaturesPlus ActiZyme - Digestive Enzymes Supplement with Probiotics, Bromelain, Lactase, Legumase - Gluten Free, Vegetarian - 90 Capsules

NaturesPlus ActiZyme Digestive Enzymes offers a comprehensive blend of digestive support. Its unique formula includes lactase and bromelain, ensuring that you can break down various foods more easily, which may reduce discomfort after meals. The inclusion of the Legumase enzyme blend specifically targets hard-to-digest fibres, helping you enjoy healthy foods without unpleasant side effects. Additionally, ActiZyme is fast-acting, allowing you to take it before or after meals for convenient digestive relief.

What We Like
Full spectrum digestive support
Targets hard-to-digest fibres
Fast-acting formula
Gluten free and vegetarian
#TOP 4

Udo's Choice Digestive Enzymes Gold - High Strength Formula

FMD045
Udo's Choice Digestive Enzymes Gold - High Strength Formula Cover
Udo's Choice Digestive Enzymes Gold - High Strength, New Formula - 9 Plant Based Digestive Enzymes - Vegetarian, Gluten Free & Dairy Free - 60 Vegecaps - One a Day

Udo's Choice Digestive Enzymes is designed to aid digestion effectively. The plant-based enzymes help break down proteins, fats, carbohydrates, and sugars, making it easier for you to digest your food. These supplements support your nutritional health by enhancing the absorption of essential nutrients, which is vital for your well-being. If you suffer from discomfort such as gas or bloating, this product offers relief and support. Additionally, the small, gluten-free vegecaps are easy to swallow, ensuring that you can take them without hassle.

What We Like
Aids digestion effectively
Enhances nutrient absorption
Provides relief from discomfort
Easy to swallow
100% vegetarian ingredients
#TOP 5

Enzymedica BeanAssist Digestive Support Capsules

31033
Enzymedica BeanAssist Digestive Support Capsules Cover
Enzymedica, BeanAssist, Digestive Support, 30 Capsules, Vegan, Gluten-Free, Soy-Free

Enzymedica BeanAssist is a nutritional supplement designed to support your digestive health. With 30 easy-to-swallow capsules, this vegan, gluten-free, and soy-free product ensures that you can maintain a balanced diet without any unwanted additives. It contains specific enzymes that help break down beans and legumes, making it easier for you to enjoy your favourite dishes without discomfort. This product is perfect for anyone looking to enhance their digestion and overall well-being.

What We Like
Vegan-friendly formulation
Gluten-free and soy-free
Supports digestive health
Easy-to-swallow capsules
Suitable for legume lovers
#TOP 6

Enzymedica Lypo Gold for Fat Digestion

981320
Enzymedica Lypo Gold for Fat Digestion Cover
Enzymedica, Lypo Gold, for Fat Digestion, Digestive Enzymes Blend, Dietary Supplement, 240 Capsules, Vegan, Gluten-Free, Soy-Free, Non-GMO

Lypo Gold is a dietary supplement designed to enhance fat digestion. It features a potent blend of lipase enzymes, which aids in breaking down dietary fats efficiently. This means you can enjoy your meals knowing your body is optimising the digestion of fats. Additionally, it promotes the absorption of essential fatty acids and fat-soluble vitamins, ensuring you gain maximum nutritional benefit from your food. Made from natural ingredients, this vegan and gluten-free product supports overall digestive health, making it a great addition to your daily routine.

What We Like
Supports fat digestion
Enhances nutrient absorption
Natural ingredients
Vegan and gluten-free
Easy-to-take capsules

MOBU Digestive Enzymes for Gut Health

DIGESTENZYME
MOBU Digestive Enzymes for Gut Health Cover
Digestive Enzymes 120 Tablets | Contains Digezyme, Amylase, Lactase, Lipase | Gut Health & Digestion Support | Vegan | UK Made | GMP Approved | MOBU

MOBU Digestive Enzymes provide an essential blend of enzymes that support the breakdown of various food components, such as lactose, proteins, carbohydrates, starches, and fats. This means you can enjoy better digestion and improved nutrient absorption, leading to enhanced overall health. The tablets are made with the highest quality standards, ensuring safety and effectiveness. Being vegan-friendly and free from gluten and dairy, these enzymes cater to a wide range of dietary needs, making them a convenient choice for many users.

What We Like
Supports optimal digestion
High-quality, UK-made product
Vegan and gluten-free
Easy to swallow tablets
#TOP 8

NaturesPlus GI Nutra Total Digestive Wellness Tablets

NaturesPlus GI Nutra Total Digestive Wellness Tablets Cover
NaturesPlus GI Nutra Total Digestive Wellness - Probiotics Supplement with Prebiotics, Digestive Enzymes, Glutamine, Calcium - Gut, Bloating - Vegetarian, Gluten Free - 90 Tablets

GI Nutra Digestive Wellness offers complete gut support, ensuring your entire digestive system is catered for. The unique microflora complex combines probiotics, prebiotics, and digestive enzymes to enhance your digestive comfort. By unlocking the potential of your food, this supplement helps you maximise the energy and nutrients from your meals. Plus, with its pure and clean formulation, free from gluten and GMOs, you can trust that you are taking a product that prioritises your health.

What We Like
Complete gut support
Unique microflora complex
Unlocks food potential
Pure and clean formulation
#TOP 9

Enzymedica Digest Basic with Probiotics

P38594
Enzymedica Digest Basic with Probiotics Cover
ENZYMEDICA - Digest Basic + Probiotics (90 Capsules) | Digestive Enzymes Supplements | Digestive Enzymes Blend with Probiotics, Nutrient Supplements, Gut Health Supplement, Easy Digest, Vegetarian

Enzymedica Digest Basic offers a comprehensive digestive enzyme and probiotic formula to help relieve occasional bloating, gas, and indigestion. This gentle yet effective blend includes 750 million CFU from nine diverse probiotic strains, enhancing your digestion and supporting regularity. With just one small capsule taken with meals, you can enjoy improved digestion of proteins, carbohydrates, dairy, fats, and fibres. The unique Thera-blend enzyme formula is designed for optimal activity across various pH levels in your digestive system, ensuring quicker relief and better overall digestion.

What We Like
Relieves bloating and gas
Supports healthy digestion
Small, easy-to-swallow capsules
Contains no harmful ingredients
#TOP 10

Healthy Origins Natural Digestive Enzymes 90 Capsules

HO-0650
Healthy Origins Natural Digestive Enzymes 90 Capsules Cover
Healthy Origins Natural Digestive Enzymes, 90 Vegan Capsules, Lab Tested, Gluten Free, Vegetarian, Soy Free, Non-GMO

Healthy Origins Digestive Enzymes provide a high-dosage formula with a 400mg enzyme blend containing 14 compatible enzymes, which can support your daily digestive health. The capsules are designed with good bioavailability, making them suitable for a vegan lifestyle, ensuring that you can easily incorporate them into your diet. Each capsule is tested in independent laboratories for quality and purity, giving you peace of mind regarding what you are consuming. They are also free from gluten, soy, and genetic engineering, allowing you to enjoy them without unwanted additives.

What We Like
High enzyme dosage per capsule
Vegan-friendly and bioavailable
Lab tested for quality assurance
Free from gluten and soy
Buying Guide Image
Editor's Notes

During our gluten-free digestive enzyme supplement research, we found 105 gluten-free digestive enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 13,748 customer reviews through our big data system to write the gluten-free digestive enzyme supplements list. We found that most customers choose gluten-free digestive enzyme supplements with an average price of £17.48.

The gluten-free digestive enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of gluten-free digestive enzyme supplements, including SOLGAR, Enzymedica, Nature's Plus, Udo's Choice, MOBU. The seller of top 1 product has received honest feedback from 257 consumers with an average rating of 4.8.

Written by
Phoebe Cooper Avatar

In 2000, Phoebe Cooper graduated from the University of London as a Pharmacist. She practiced as a Pharmacist for the better part of 2 decades. Phoebe says she has worked in the majority of health sectors and has sufficient accumulated knowledge and experience. In her practice, Phoebe published a series of eBooks, one of which is titled "Good Health Good Living."