Best Digestive Enzyme Supplements of 2025

Phoebe Cooper Avatar
Phoebe Cooper
Last Updated: 2 Feb 2025

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Digestive Enzyme Supplements are dietary supplements that contain enzymes that help break down food molecules into smaller, more easily absorbable components. These supplements are designed to support healthy digestion and are often used by individuals who have trouble digesting certain types of food, such as those with lactose intolerance or gluten sensitivity. Digestive Enzyme Supplements come in various forms, including capsules, tablets, and powders, and may contain a blend of different enzymes to target specific types of food. While these supplements are not intended to replace a healthy diet, they can provide additional support for those who need it.

At a Glance: Our Top Picks

Natures Aid Digestive Enzyme Complex with Betaine Cover #TOP 1
Natures Aid Digestive Enzyme Complex with Betaine
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Solgar Digestive Enzymes for Nutrient Absorption Cover #TOP 2
Solgar Digestive Enzymes for Nutrient Absorption
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Digestive Enzymes and Probiotic Supplement for Comfort Cover #TOP 3
Digestive Enzymes and Probiotic Supplement for Comfort
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Top 10 Digestive Enzyme Supplements

Natures Aid Digestive Enzyme Complex with Betaine

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Natures Aid Digestive Enzyme Complex with Betaine Cover
Natures Aid Digestive Enzyme Complex with Betaine Hydrochloride, Vegan, 60 Tablets

Natures Aid Enzyme Complex is a carefully formulated blend of enzymes, including Amylase, Protease, Lipase, Lactase, and Cellulose, along with Betaine Hydrochloride. These ingredients work together to support your digestive health, making it easier for you to break down food effectively. The inclusion of lactase enzymes is particularly beneficial for those who experience difficulty digesting lactose, allowing for more comfortable meals. Additionally, taking just 1-2 tablets during mealtimes ensures you receive the support you need without hassle. Made in the UK to high standards, this product is suitable for both vegetarians and vegans.

What We Like
Supports digestive health
Helps with lactose digestion
Convenient daily dosage
Suitable for vegans
Made in the UK

Solgar Digestive Enzymes for Nutrient Absorption

E1001
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Solgar Digestive Enzymes for Nutrient Absorption Cover
Solgar Digestive Enzymes Tablets - Pack of 250 - Helps Extract Nutrients from Food - Gluten Free

Solgar Digestive Enzymes support your digestive system by helping you break down food and absorb essential nutrients. By taking 1-3 tablets daily, you enhance your body's ability to digest what you eat. The holistic formula includes various enzymes like ox bile and papain, each targeting different food groups for improved digestion. Moreover, Solgar is committed to sustainability with recyclable packaging, ensuring that you can feel good about your purchase while caring for the planet.

What We Like
Improves digestion and nutrient absorption
Holistic enzyme blend
Sustainable packaging
Crafted in small batches

Digestive Enzymes and Probiotic Supplement for Comfort

MAV NUTRITION
Digestive Enzymes and Probiotic Supplement for Comfort Cover
Digestive Enzymes & Probiotic Supplement | Enzymes for Digestion Aid, Bloating, IBS, Constipation and Gas Relief | 60 Premium Enzymes Blend Capsules

MAV NUTRITION Digestive Enzymes offer ultimate digestive comfort by aiding your body in breaking down proteins, fats, and carbohydrates, which enhances nutrient absorption and reduces discomfort. This supplement also provides relief from gas and bloating, particularly after consuming hard-to-digest foods. Additionally, it supports gut health by incorporating three potent strains of beneficial bacteria, crucial for overall wellness. Lastly, it boosts your energy levels by ensuring efficient digestion, allowing you to absorb more energising nutrients and maintain an active lifestyle.

What We Like
Reduces gas and bloating
Supports gut health
Boosts energy levels
Enhances nutrient absorption

MOBU Digestive Enzymes for Gut Health

DIGESTENZYME
MOBU Digestive Enzymes for Gut Health Cover
Digestive Enzymes 120 Tablets | Contains Digezyme, Amylase, Lactase, Lipase | Gut Health & Digestion Support | Vegan | UK Made | GMP Approved | MOBU

MOBU Digestive Enzymes provide an essential blend of enzymes that support the breakdown of various food components, such as lactose, proteins, carbohydrates, starches, and fats. This means you can enjoy better digestion and improved nutrient absorption, leading to enhanced overall health. The tablets are made with the highest quality standards, ensuring safety and effectiveness. Being vegan-friendly and free from gluten and dairy, these enzymes cater to a wide range of dietary needs, making them a convenient choice for many users.

What We Like
Supports optimal digestion
High-quality, UK-made product
Vegan and gluten-free
Easy to swallow tablets

Pure Encapsulations Digestive Enzymes Ultra Supplement

Pure Encapsulations Digestive Enzymes Ultra Supplement Cover
Pure Encapsulations - Digestive Enzymes Ultra with Betaine HCl - Broad Spectrum Vegetarian Digestive Enzymes - Lactose, Protein & Fat Digestion - 90 Capsules

Digestive Enzymes Ultra is a high-strength, broad-spectrum vegetarian supplement designed to support your digestion. It contains enzymes that help break down proteins, carbohydrates, fats, fibre, and lactose, making it easier for you to digest various foods. The inclusion of lipase aids in the breakdown of dietary fats, while lactase specifically targets lactose in dairy products, promoting comfort for those sensitive to lactose. With a 45-day supply, simply take two capsules with each meal to enhance your digestive health.

What We Like
High-strength vegetarian enzymes
Aids in fat and lactose digestion
45-day supply per bottle
Premium ingredients used
Free from common allergens
#TOP 6

Zenwise Health Digestive Enzymes and Probiotics

Zenwise Health
810030591504
Zenwise Health Digestive Enzymes and Probiotics Cover
Zenwise Health Digestive Enzymes + Probiotics for Gut Health and Prebiotics Fibre Supplements for Bloating Relief and Digestion - 100 Count

Zenwise Digestive Support offers complete digestive care by combining plant-based enzymes, probiotics, and prebiotics. This unique blend helps to optimise your digestion and reduce bloating, ensuring you feel more comfortable after meals. The natural gas relief feature effectively breaks down hard-to-digest foods, preventing excess gas and discomfort. Additionally, the product fosters a healthy gut environment by feeding beneficial microflora, allowing probiotics to thrive in your digestive tract.

What We Like
Reduces bloating effectively
Supports digestive health
Helps eliminate gas
Promotes healthy gut flora
#TOP 7

Viridian High Potency Vegan Digestive Aid

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Viridian High Potency Vegan Digestive Aid Cover
Viridian: High Potency Digestive Aid (Vegan) 150 Veg Caps

The Viridian Digestive Aid is a high potency nutritional supplement designed to support your digestive health. With 150 vegan capsules in each pack, this product ensures that you have an ample supply to promote digestive efficiency. It contains betaine, which is known for its beneficial effects on digestion, helping you to feel more comfortable after meals. By incorporating this supplement into your routine, you can enhance your overall digestive wellbeing and enjoy greater convenience in maintaining a healthy lifestyle.

What We Like
High potency formula
Vegan-friendly
Contains betaine for digestion
150 capsules per pack
#TOP 8

SuperSelf Digestive Enzyme Supplements with Betaine HCL

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SuperSelf Digestive Enzyme Supplements with Betaine HCL Cover
Digestive Enzyme Supplements with Betaine HCL - 7 Digestive Enzymes for Gut Health & Support with Lactase, Bromelain, Lipase & Peppermint Oil - 30 Capsules - Gentle & Fast Acting Tablets - UK Made

SuperSelf Digestive Enzymes provide essential support for your digestive system. By taking these supplements at mealtimes, you can reduce discomfort linked to enzyme deficiencies and improve nutrient absorption. The unique blend of seven powerful enzymes, along with betaine HCL and peppermint oil, offers rapid and gentle digestive assistance. Each carefully selected ingredient works to break down food more effectively, making it easier for your body to digest proteins, fats, and carbohydrates.

What We Like
Reduces digestive discomfort
Enhances nutrient absorption
Contains seven digestive enzymes
Gentle and fast-acting formula
High quality and reliable
#TOP 9

Freak Athletics Digestive Enzyme Capsules

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Freak Athletics Digestive Enzyme Capsules Cover
Digestive Enzyme Supplements - 180 Capsules Digestive Enzymes with Plant Based Ingredients - Supports Gut and Daily Digestive Health

Dive into better digestive health with Freak Athletics Digestive Enzymes. These capsules support your body in breaking down proteins, carbohydrates, and fats, making nutrients easier for you to absorb. With a blend of premium ingredients like Betaine HCL and Bromelain, you can trust that you’re getting an optimal formula for your needs. Manufactured in the UK to the highest standards, these supplements ensure you receive quality you can rely on. Experience the commitment to your health and wellbeing with every capsule.

What We Like
Supports nutrient absorption
High-quality plant-based ingredients
Manufactured in the UK
Optimal formula for digestive health
#TOP 10

Pure Encapsulations Digestive Enzymes Ultra Supplement

Pure Encapsulations Digestive Enzymes Ultra Supplement Cover
Pure Encapsulations - Digestive Enzymes Ultra - Broad Spectrum Vegetarian Digestive Enzymes - 90 Capsules

Pure Encapsulations Digestive Enzymes Ultra is designed to support your digestion with a high-strength, broad-spectrum of vegetarian enzymes. By taking two capsules with each meal, you can effectively break down proteins, carbohydrates, fats, fibres, and lactose, helping to ease discomfort after meals. This supplement also promotes the digestion of fatty foods, making it easier for your body to process rich dishes. Additionally, it is made from premium, carefully sourced ingredients, ensuring you receive a product that is both potent and pure.

What We Like
High-strength vegetarian enzymes
Supports digestion of fats
Easy to take with meals
Premium quality ingredients
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Are digestive enzyme supplements good for you?

“Overall, a healthy person really doesn't need to take digestive enzyme supplements,” Denhard explains. “The best digestive enzymes are the ones our bodies make naturally, and they work best when you eat a whole food diet.”

2. Is it OK to take digestive enzymes every day?

When taken in recommended doses, most digestive enzyme supplements are considered safe. Some people can experience side effects like nausea, stomach pain, diarrhea, and vomiting. Others may have an allergic reaction.

3. What is the most effective digestive enzyme?

Best Overall: Pure Encapsulations Digestive Enzymes Ultra Each serving of Pure Encapsulations' Digestive Enzymes Ultra provides 391 milligrams of the proprietary enzyme blend, which includes 13 digestive enzymes, including protease, lipase, and amylase.

4. Can you take digestive enzymes with vitamins?

Yes, but just make sure that you take digestive enzymes together with meals and therapeutic enzymes together on an empty stomach (30 minutes before or 2 hours after eating). Can probiotics be taken with enzyme supplements? Yes and probiotics actually help manufacture enzymes for the body.

Editor's Notes

During our digestive enzyme supplement research, we found 233 digestive enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 258,562 customer reviews through our big data system to write the digestive enzyme supplements list. We found that most customers choose digestive enzyme supplements with an average price of £17.24.

The digestive enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of digestive enzyme supplements, including Natures Aid, SOLGAR, MAV NUTRITION, MOBU, Pure Encapsulations.

Written by
Phoebe Cooper Avatar

In 2000, Phoebe Cooper graduated from the University of London as a Pharmacist. She practiced as a Pharmacist for the better part of 2 decades. Phoebe says she has worked in the majority of health sectors and has sufficient accumulated knowledge and experience. In her practice, Phoebe published a series of eBooks, one of which is titled "Good Health Good Living."