Best Thumb Button Mice of 2025

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Thumb button mice are a type of computer mouse that are designed with additional buttons located on the side of the device, near where the user's thumb rests. These extra buttons can be programmed to perform specific functions, such as navigating back and forth through web pages or documents, or adjusting the volume on a computer. Thumb button mice are popular among gamers and professionals who require quick access to frequently used commands. They can help to improve productivity and reduce strain on the hand and wrist, making them a valuable addition to any computer setup.
At a Glance: Our Top Picks
Top 10 Thumb Button Mice
Trust Voca Wired Computer Mouse with DPI Options
The Trust Voca Mouse is designed for comfort and ease of use. Its ergonomic shape allows for a relaxed grip, making long hours at the computer more enjoyable. You can easily select your preferred speed from four DPI settings—800, 1200, 1600, or 2400—giving you control over your cursor movement. With a simple plug and play USB connection, you can start using the mouse without any hassle. Additionally, the two thumb buttons for browser navigation enhance your browsing experience, allowing you to quickly go back or forward with ease.
Trust Fyda Ergonomic USB Mouse with DPI Control
The Trust Fyda Mouse features an ergonomic design that provides hours of working comfort, making it ideal for long tasks. Its sustainable construction, made with recycled materials, allows you to feel good about your choice while being eco-friendly. The sculpted shape includes thumb and little finger rests, providing excellent support for your hand and reducing strain. Additionally, with six buttons, including two for easy thumb access, you can navigate with convenience, improving your productivity.
Trust Fyda Rechargeable Ergonomic Wireless Mouse
The Trust Fyda Mouse provides a fully wireless experience, eliminating the need for disposable batteries. Its rechargeable feature and 10m range ensure convenience for users on the go. Made from 50% recycled materials, you can feel good about your choice while working with peace of mind. The all-day comfort design includes thumb and finger rests, offering better hand support for extended use. Additionally, you can easily adjust the DPI settings between 800 and 2400 to suit your preferences and tasks, enhancing your precision.
ELECOM EX-G Left Handed Trackball Mouse
The ELECOM EX-G Trackball Mouse is designed specifically for left-handed users, offering precise cursor movement for enhanced productivity. With six programmable buttons, you can easily customise functions to suit your workflow. The DPI button allows you to switch between 750 and 1500 DPI, providing flexibility for quicker or slower cursor movements. Additionally, the trackball's large artificial ruby ball bearings ensure smooth operation and easy maintenance, as they resist dust build-up. This mouse combines comfort and functionality for an improved user experience.
Elecom EX-G Ergonomic Trackball Mouse
The Elecom EX-G Mouse features an ergonomic design tailored to the natural movements of your hand, enhancing comfort during prolonged use. Its unique red trackball offers precise control, making it ideal for high-performance tasks such as gaming. With six functional buttons, including a tilting scroll wheel, navigating documents and web pages becomes effortless. You can easily adjust the DPI settings between 750 and 1500, allowing you to optimise cursor speed for different tasks.
Trust Nito Ergonomic Wireless Mouse with Thumb Rest
The Trust Nito Wireless Mouse is designed with an ergonomic shape to ensure comfortable use throughout long workdays. Its thumb rest features a rubber inlay for a secure grip, providing added comfort while you work. With a wireless range of up to 10 metres, you can enjoy freedom of movement without the hassle of cords. You can also adjust the cursor speed between 800 and 2200 DPI, allowing you to tailor your mouse sensitivity to your specific needs, making tasks smoother and more efficient.
Speedlink LIBERA Rechargeable Wireless Silent Mouse
The Speedlink LIBERA Mouse offers versatile connectivity for your laptop or PC, allowing you to connect via Bluetooth or a USB-A 2.4 GHz nano receiver. Its compact design features five buttons and a DPI switch, enabling you to adjust the sensitivity to suit your needs, enhancing your control. You'll appreciate the dual scroll wheels that facilitate effortless side-to-side scrolling, making it easy to navigate through documents and web pages. Additionally, the silent clicking ensures a quiet work environment, allowing you to focus without distractions.
Trust Verto Wireless Ergonomic Vertical Mouse
The Trust Verto Mouse is designed to reduce strain and discomfort while you work. Its ergonomic shape positions your arm and wrist at a natural 60°, making it easier for you to work for longer periods without pain. The lightweight design fits all hand sizes, offering a thumb rest and a rubber coating for improved grip and comfort. With a wireless range of 10 metres, you can enjoy greater freedom of movement, allowing you to maintain better posture while you work.
Trust Verto Ergonomic Vertical Mouse with LED
The Trust Verto Mouse is designed to combat strain and discomfort during use. Its ergonomic shape positions your arm and wrist at a natural 60°, allowing you to work effortlessly. You will feel the difference with its lightweight design and comfortable thumb rest, providing a secure grip for all hand sizes. The accurate 1000/1600 DPI optical sensor, along with two thumb buttons, ensures that you have precise control over your tasks. Plus, the plug-and-play feature means you can connect it easily and start working right away.
INFINMIND Wireless Bluetooth Mouse with Ergonomic Design
The INFINMIND Wireless Mouse offers a seamless experience with its 4-level DPI settings, ensuring you can adjust the sensitivity to suit your needs for both work and leisure. The smart flying scroll feature allows you to navigate pages swiftly and quietly, enhancing your productivity. Designed with comfort in mind, it reduces hand fatigue, making it ideal for long hours of use. Additionally, you can easily connect to three devices, switching between them effortlessly, which is perfect for multitasking on different computers.
Frequently Asked Questions (FAQs)
1. What is the thumb button on mouse?
Use the mouse side buttons These buttons can be programmed to do anything. However, by default, the left-thumb button can go back on a web page. Using the thumb button makes browsing the Internet more efficient, because you do not need to move the mouse pointer to the browser's back arrow button to go back a page.
2. Which button is mouse 4?
The “4” mouse button is the fifth button on the user's mouse if this additional button exists, for example, volume buttons on the mouse. Unity defines this as the "4" Mouse button, as the mouse Button numbering begins at 0.
During our thumb button mice research, we found 101 thumb button mice products and shortlisted 10 quality products. We collected and analyzed 205,667 customer reviews through our big data system to write the thumb button mice list. We found that most customers choose thumb button mice with an average price of £19.22.
The thumb button mice are available for purchase. We have researched hundreds of brands and picked the top brands of thumb button mice, including Trust, Elecom, Speedlink, INFINMIND.

Kenneth Collin graduated from Imperial College, London, at 22. He is a UX/UI designer, a web developer, and a writer, amongst others. At age 14, Kenneth programmed his first app. Kenneth's app served as a remote control for censored devices. "When I was 8, I would pick up scraps from electronics and try to rebuild or at least fix them," Kenneth said in one of his recent articles on Home repairs for top gadgets.