Best Programmable Buttons Mice of 2025

Kenneth Collin Avatar
Kenneth Collin
Last Updated: 31 Jan 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Programmable buttons mice are computer mice that come equipped with extra buttons that can be programmed to perform specific functions. These mice are designed to provide users with greater flexibility and control over their computing experience. With programmable buttons, users can customise their mouse to suit their specific needs, whether it be for gaming, graphic design, or simply for everyday use. These mice come in a range of styles and sizes to accommodate different preferences and needs, and are a great option for those looking to maximise their productivity and efficiency.

At a Glance: Our Top Picks

Razer DeathAdder Essential Wired Gaming Mouse Cover #TOP 1
Razer DeathAdder Essential Wired Gaming Mouse
ftb score rating icon 9.9
SUMVISION RAIJIN Wired Gaming Mouse with RGB Cover #TOP 2
SUMVISION RAIJIN Wired Gaming Mouse with RGB
ftb score rating icon 9.8
HP 420 Wireless Mouse with Programmable Buttons Cover #TOP 3
HP 420 Wireless Mouse with Programmable Buttons
ftb score rating icon 9.6

Top 10 Programmable Buttons Mice

Razer DeathAdder Essential Wired Gaming Mouse

RZ01-03850100-R3M1
Black
12.7 x 7.3 x 4.3 cm
Razer DeathAdder Essential Wired Gaming Mouse Cover
Razer DeathAdder Essential (2021) - Wired Gaming Mouse (Optical Sensor, 6400 DPI, 5 Programmable Buttons, Ergonomic Form Factor) Black

The Razer DeathAdder Essential is an exceptional wired gaming mouse designed to enhance your gaming experience. Its true 6,400 DPI optical sensor ensures fast and precise swipes, allowing you to stay in control during intense gameplay. With an ergonomic form, you can enjoy extended gaming sessions in comfort, preventing fatigue. Additionally, the mouse boasts high durability, built to withstand even the most intense gaming marathons, while its five Hyperesponse buttons are tested for up to 10 million clicks, ensuring reliable performance throughout your gaming adventures.

What We Like
High precision with 6,400 DPI
Comfortable ergonomic design
Durable for long gaming sessions
Responsive buttons for quick actions

SUMVISION RAIJIN Wired Gaming Mouse with RGB

RaijinX
Black
SUMVISION RAIJIN Wired Gaming Mouse with RGB Cover
Gaming Mouse SUMVISION RAIJIN Computer Mouse 12,400 DPI 16.8 Million Colour 30G Programmable Buttons Macro Software Ergonomic Wired Mouse For PC Laptop Apple Mac Windows 11 (UK DESIGN UK TECH SUPPORT)

The SUMVISION RAIJIN Mouse offers an ultra-light honeycomb mesh design, ensuring comfort during long gaming sessions while reducing sweat. With fully customisable RGB LED lights, you can change the mouse's colour to match your mood or gaming setup. The adjustable 12,400 DPI allows for quick adjustments, making it easier to respond to in-game situations. Additionally, the programmable macro editor lets you customise button functions, providing enhanced control and convenience for your gameplay.

What We Like
Lightweight and comfortable design
Customisable RGB lighting
High DPI for quick response
Programmable buttons for flexibility
#TOP 3

HP 420 Wireless Mouse with Programmable Buttons

HP
HP Laptop
Black
HP 420 Wireless Mouse with Programmable Buttons Cover
HP 420 Programmable Wireless Mouse, Compatible with Chrome, PC or Mac, Bluetooth 5.3, 6 Programmable Buttons, 4000 DPI Multi-Surface Sensor, AES technology, Up to 24 Months Battery, Black

The HP 420 Mouse offers seamless connectivity to up to three devices, making it incredibly versatile for your daily tasks. With its high sensitivity of 4000 DPI, you can track accurately on various surfaces, enhancing your productivity. Enjoy the convenience of up to 24 months of battery life from a single AA battery, meaning less time worrying about replacements. Additionally, customise your experience by programming six buttons through the HP Accessory Centre app, allowing you to streamline your workflow with your favourite shortcuts.

What We Like
Seamless multi-device connectivity
Long battery life
Customisable buttons
High sensitivity tracking
Quiet clicking feature
#TOP 4

Trust Voxx Vertical Ergonomic Wireless Mouse

23731
Black
Trust Voxx Vertical Ergonomic Wireless Mouse Cover
Trust Voxx Vertical Ergonomic Mouse, Rechargeable Wireless Mouse, Bluetooth or 2.4 GHz, 1200-2400 DPI, 9 Buttons, LED Display, Programmable Buttons, for PC, Computer, Mac, Laptop, Chromebook - Black

The Trust Voxx Ergonomic Mouse is designed with your comfort in mind. Its vertical shape reduces strain on your arm and wrist, allowing you to work for hours without discomfort. You can choose how to connect it, whether via USB cable, USB receiver, or Bluetooth, giving you flexibility. The rechargeable battery and energy-saving on/off switch promote sustainable use. Additionally, the LED display keeps you informed of button functionality, DPI settings, connection status, and battery life, enhancing your overall user experience.

What We Like
Ergonomic design for comfort
Multiple connectivity options
Rechargeable battery
Informative LED display
Customisable programmable buttons
#TOP 5

Perixx PERIMICE 608 Wireless Vertical Mouse

10914
Black
Wireless
Perixx PERIMICE 608 Wireless Vertical Mouse Cover
Perixx PERIMICE 608 Wireless Ergonomic Vertical Mouse - 5 Programmable Buttons - 800/1200/1600 DPI – Recommended with RSI User - Black

The Perixx PERIMICE 608 Mouse is an ergonomic wireless vertical mouse designed to enhance comfort during extended computer use. With its 2.4 GHz wireless technology, you can enjoy a seamless connection up to 10 meters away. The integrated DPI switch allows you to easily adjust sensitivity between 800, 1200, and 1600 DPI, providing flexibility for different tasks. Its right-handed design helps reduce the risk of RSI, making it ideal for office workers and gamers alike. Additionally, the mouse features five programmable buttons, allowing you to customise your experience for maximum efficiency.

What We Like
Ergonomic design reduces wrist strain
Adjustable DPI for flexibility
Wireless technology with good range
Five programmable buttons
Compact USB receiver storage
#TOP 6

Acer Ergonomic Wired USB Optical Mouse

OMW313
black
Acer Ergonomic Wired USB Optical Mouse Cover
acer Wired USB Mouse, Ergonomic Wired PC Mouse, USB Optical Mouse with 6 Programmable Buttons, 3200 DPI, Compatible with PC, Mac, Laptop, Chromebook

The Acer Wired Mouse offers high precision and durability, ensuring accurate cursor control on different surfaces. With four adjustable DPI levels, you can easily switch between speeds to suit your tasks, enhancing your productivity. The six programmable buttons allow you to navigate through websites effortlessly, making your browsing experience more efficient. Additionally, the ergonomic design fits comfortably in your hand, reducing muscle strain and preventing fatigue during extended use.

What We Like
High precision tracking
Four DPI adjustment levels
Ergonomic design for comfort
Plug-and-play convenience
#TOP 7

ASUS ROG Spatha X Wireless Gaming Mouse

90MP0220-BMUA00
Black
ASUS ROG Spatha X Wireless Gaming Mouse Cover
ASUS ROG Spatha X Wireless Gaming Mouse, 24 GHz/Wired USB, 19,000 DPI Optical Sensor, 12 Programmable Buttons, RGB, Swappable Switch Design, Micro Switches, Magnetic Charging Stand, Black

The ASUS ROG Spatha X is designed for gamers who demand precision and customisation. With its 12 programmable buttons, you can tailor your gameplay to suit your style, giving you an edge in competitive situations. The industry-leading 19,000 dpi optical sensor ensures that your movements are accurately translated on-screen, enhancing your gaming experience. Wireless mode offers an impressive battery life of up to 67 hours with RGB off, allowing you to play without interruptions. Plus, the exclusive push-fit switch sockets let you customise click force, prolonging the lifespan of your mouse.

What We Like
Highly customisable button layout
High precision 19,000 dpi sensor
Long battery life
Durable switch design
#TOP 8

Logitech M720 Triathlon Wireless Mouse with Bluetooth

910-004791
Black/White
Logitech M720 Triathlon Wireless Mouse with Bluetooth Cover
Logitech M720 Triathlon Multi-Device Wireless Mouse, Bluetooth, USB Unifying Receiver, 1000 DPI, 6 Programmable Buttons, 2-Year Battery, Compatible with Laptop, PC, Mac, iPadOS - Grey

The Logitech M720 Mouse is designed for endurance, boasting a remarkable 24-month battery life, making it ideal for long-term use without frequent charging. Its comfortable grip ensures that you can work for hours without discomfort, thanks to its sculpted design tailored for right-handed users. The hyper-fast scrolling feature allows you to navigate through lengthy documents and web pages with ease, increasing your productivity. Additionally, with dual connectivity options, you can seamlessly connect this mouse via Bluetooth or the Logitech Unifying receiver, simplifying your setup.

What We Like
Long battery life
Comfortable ergonomic design
Hyper-fast scrolling
Dual connectivity options
Multi-device compatibility
#TOP 9

HP G360 RGB Wired Gaming Mouse with 6 Buttons

HP
G360
Black
HP G360 RGB Wired Gaming Mouse with 6 Buttons Cover
HP G360 RGB Backlighting USB Wired Gaming Mouse with 6 Programmable Buttons, Customizable 6200 DPI, Ergonomic Design, Non-Slip 3D Roller/ 3 Years Warranty (4QM92AA)

The HP G360 Gaming Mouse is designed for gamers seeking precision and customisation. With six DPI sensitivity settings, you can instantly switch between levels for more accurate targeting in your games. The mouse supports the customisation of all keys, allowing you to tailor your controls to your preferences. Its maximum DPI of 6200 ensures a responsive experience, making every movement count. Additionally, the ergonomic design ensures comfort during extended gameplay sessions, reducing strain on your hand.

What We Like
Customisable DPI settings
Ergonomic design for comfort
Six programmable buttons
Compatible with multiple Windows versions
#TOP 10

Uineer Wired Silent Mouse with 4800DPI

Uineer
PB1-BLACK
Black
Uineer Wired Silent Mouse with 4800DPI Cover
Wired Mouse, PC silent mouse, 4800DPI Adjustable & 6 Programmable Buttons, Ergonomic Design, Streamlined USB Wired Mouse for PC Laptop Computer(Pink)

The Uineer Wired Mouse offers excellent features for any computer user. With six programmable buttons, you can customise your mouse for quick access to your most-used functions, enhancing your productivity. The four-colour dynamic breathing light not only adds style but also allows you to personalise your workspace. You can easily adjust the DPI settings from 1200 to 4800, providing high precision for both gaming and everyday tasks. Its ergonomic and silent design ensures comfort during long hours of use, making it a great choice for a peaceful environment.

What We Like
Six programmable buttons
Customisable lighting effects
Adjustable DPI settings
Ergonomic and silent design
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What are programmable buttons on a mouse?

Programmable button mouse (PBM) is an input device, which can be generally programmed to do specific tasks. PBM is widely used in the gaming arena because a number of tasks or actions in gaming that usually require the use of a number of keyboard keys can be accomplished by a single click with PBM.

2. Can you reprogram buttons on a mouse?

To reassign a button across all applications Using the mouse that you want to configure, start Microsoft Mouse and Keyboard Center. Select basic settings. Select the button that you want to reassign. In the list of the button that you want to reassign, select a command.

Editor's Notes

During our programmable buttons mice research, we found 140 programmable buttons mice products and shortlisted 10 quality products. We collected and analyzed 156,931 customer reviews through our big data system to write the programmable buttons mice list. We found that most customers choose programmable buttons mice with an average price of £15.03.

The programmable buttons mice are available for purchase. We have researched hundreds of brands and picked the top brands of programmable buttons mice, including Razer, Sumvision, HP, Trust, perixx.

Written by
Kenneth Collin Avatar

Kenneth Collin graduated from Imperial College, London, at 22. He is a UX/UI designer, a web developer, and a writer, amongst others. At age 14, Kenneth programmed his first app. Kenneth's app served as a remote control for censored devices. "When I was 8, I would pick up scraps from electronics and try to rebuild or at least fix them," Kenneth said in one of his recent articles on Home repairs for top gadgets.