Best Programmable Buttons Mice of 2025

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Programmable buttons mice are computer mice that come equipped with extra buttons that can be programmed to perform specific functions. These mice are designed to provide users with greater flexibility and control over their computing experience. With programmable buttons, users can customise their mouse to suit their specific needs, whether it be for gaming, graphic design, or simply for everyday use. These mice come in a range of styles and sizes to accommodate different preferences and needs, and are a great option for those looking to maximise their productivity and efficiency.
At a Glance: Our Top Picks
Top 10 Programmable Buttons Mice
Razer DeathAdder Essential Wired Gaming Mouse
The Razer DeathAdder Essential is an exceptional wired gaming mouse designed to enhance your gaming experience. Its true 6,400 DPI optical sensor ensures fast and precise swipes, allowing you to stay in control during intense gameplay. With an ergonomic form, you can enjoy extended gaming sessions in comfort, preventing fatigue. Additionally, the mouse boasts high durability, built to withstand even the most intense gaming marathons, while its five Hyperesponse buttons are tested for up to 10 million clicks, ensuring reliable performance throughout your gaming adventures.
SUMVISION RAIJIN Wired Gaming Mouse with RGB
The SUMVISION RAIJIN Mouse offers an ultra-light honeycomb mesh design, ensuring comfort during long gaming sessions while reducing sweat. With fully customisable RGB LED lights, you can change the mouse's colour to match your mood or gaming setup. The adjustable 12,400 DPI allows for quick adjustments, making it easier to respond to in-game situations. Additionally, the programmable macro editor lets you customise button functions, providing enhanced control and convenience for your gameplay.
HP 420 Wireless Mouse with Programmable Buttons
The HP 420 Mouse offers seamless connectivity to up to three devices, making it incredibly versatile for your daily tasks. With its high sensitivity of 4000 DPI, you can track accurately on various surfaces, enhancing your productivity. Enjoy the convenience of up to 24 months of battery life from a single AA battery, meaning less time worrying about replacements. Additionally, customise your experience by programming six buttons through the HP Accessory Centre app, allowing you to streamline your workflow with your favourite shortcuts.
Trust Voxx Vertical Ergonomic Wireless Mouse
The Trust Voxx Ergonomic Mouse is designed with your comfort in mind. Its vertical shape reduces strain on your arm and wrist, allowing you to work for hours without discomfort. You can choose how to connect it, whether via USB cable, USB receiver, or Bluetooth, giving you flexibility. The rechargeable battery and energy-saving on/off switch promote sustainable use. Additionally, the LED display keeps you informed of button functionality, DPI settings, connection status, and battery life, enhancing your overall user experience.
Perixx PERIMICE 608 Wireless Vertical Mouse
The Perixx PERIMICE 608 Mouse is an ergonomic wireless vertical mouse designed to enhance comfort during extended computer use. With its 2.4 GHz wireless technology, you can enjoy a seamless connection up to 10 meters away. The integrated DPI switch allows you to easily adjust sensitivity between 800, 1200, and 1600 DPI, providing flexibility for different tasks. Its right-handed design helps reduce the risk of RSI, making it ideal for office workers and gamers alike. Additionally, the mouse features five programmable buttons, allowing you to customise your experience for maximum efficiency.
Acer Ergonomic Wired USB Optical Mouse
The Acer Wired Mouse offers high precision and durability, ensuring accurate cursor control on different surfaces. With four adjustable DPI levels, you can easily switch between speeds to suit your tasks, enhancing your productivity. The six programmable buttons allow you to navigate through websites effortlessly, making your browsing experience more efficient. Additionally, the ergonomic design fits comfortably in your hand, reducing muscle strain and preventing fatigue during extended use.
ASUS ROG Spatha X Wireless Gaming Mouse
The ASUS ROG Spatha X is designed for gamers who demand precision and customisation. With its 12 programmable buttons, you can tailor your gameplay to suit your style, giving you an edge in competitive situations. The industry-leading 19,000 dpi optical sensor ensures that your movements are accurately translated on-screen, enhancing your gaming experience. Wireless mode offers an impressive battery life of up to 67 hours with RGB off, allowing you to play without interruptions. Plus, the exclusive push-fit switch sockets let you customise click force, prolonging the lifespan of your mouse.
Logitech M720 Triathlon Wireless Mouse with Bluetooth
The Logitech M720 Mouse is designed for endurance, boasting a remarkable 24-month battery life, making it ideal for long-term use without frequent charging. Its comfortable grip ensures that you can work for hours without discomfort, thanks to its sculpted design tailored for right-handed users. The hyper-fast scrolling feature allows you to navigate through lengthy documents and web pages with ease, increasing your productivity. Additionally, with dual connectivity options, you can seamlessly connect this mouse via Bluetooth or the Logitech Unifying receiver, simplifying your setup.
HP G360 RGB Wired Gaming Mouse with 6 Buttons
The HP G360 Gaming Mouse is designed for gamers seeking precision and customisation. With six DPI sensitivity settings, you can instantly switch between levels for more accurate targeting in your games. The mouse supports the customisation of all keys, allowing you to tailor your controls to your preferences. Its maximum DPI of 6200 ensures a responsive experience, making every movement count. Additionally, the ergonomic design ensures comfort during extended gameplay sessions, reducing strain on your hand.
Uineer Wired Silent Mouse with 4800DPI
The Uineer Wired Mouse offers excellent features for any computer user. With six programmable buttons, you can customise your mouse for quick access to your most-used functions, enhancing your productivity. The four-colour dynamic breathing light not only adds style but also allows you to personalise your workspace. You can easily adjust the DPI settings from 1200 to 4800, providing high precision for both gaming and everyday tasks. Its ergonomic and silent design ensures comfort during long hours of use, making it a great choice for a peaceful environment.
Frequently Asked Questions (FAQs)
1. What are programmable buttons on a mouse?
Programmable button mouse (PBM) is an input device, which can be generally programmed to do specific tasks. PBM is widely used in the gaming arena because a number of tasks or actions in gaming that usually require the use of a number of keyboard keys can be accomplished by a single click with PBM.
2. Can you reprogram buttons on a mouse?
To reassign a button across all applications Using the mouse that you want to configure, start Microsoft Mouse and Keyboard Center. Select basic settings. Select the button that you want to reassign. In the list of the button that you want to reassign, select a command.
During our programmable buttons mice research, we found 140 programmable buttons mice products and shortlisted 10 quality products. We collected and analyzed 156,931 customer reviews through our big data system to write the programmable buttons mice list. We found that most customers choose programmable buttons mice with an average price of £15.03.
The programmable buttons mice are available for purchase. We have researched hundreds of brands and picked the top brands of programmable buttons mice, including Razer, Sumvision, HP, Trust, perixx.

Kenneth Collin graduated from Imperial College, London, at 22. He is a UX/UI designer, a web developer, and a writer, amongst others. At age 14, Kenneth programmed his first app. Kenneth's app served as a remote control for censored devices. "When I was 8, I would pick up scraps from electronics and try to rebuild or at least fix them," Kenneth said in one of his recent articles on Home repairs for top gadgets.