Best Ergonomic Mice of 2025

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Ergonomic mice are computer mice designed to reduce the discomfort and strain caused by traditional mice. These mice are specially designed to fit the natural hand movements of the user, allowing for a more comfortable and efficient computing experience. With a range of shapes, sizes and features, ergonomic mice offer a variety of options to suit different users and preferences. They are recommended for those who spend long hours working on a computer, or those who experience discomfort or pain in their hands or wrist.
At a Glance: Our Top Picks
Top 10 Ergonomic Mice
Anker AK-UBA Wireless Vertical Ergonomic Mouse
The Anker AK-UBA Mouse features a scientific ergonomic design that promotes a healthy wrist and arm position, helping to reduce strain during long periods of use. With adjustable DPI settings of 800, 1200, and 1600, you can enjoy smooth and precise tracking on various surfaces, making it ideal for everyday tasks. The added next and previous buttons enhance your browsing experience, providing convenience for internet surfing or gaming. Additionally, the mouse enters power-saving mode after 8 minutes of inactivity, ensuring longer battery life and efficiency.
Logitech Lift Vertical Ergonomic Mouse Graphite
The Logitech Lift Mouse is designed to enhance your comfort while working. Its vertical shape promotes a natural wrist posture, helping you feel relaxed throughout the day. You can enjoy a snug thumb rest and a softly textured grip, making long hours at your desk much more pleasant. Additionally, the mouse features whisper-quiet clicks and customisable buttons, allowing you to focus on your tasks without distractions.
TECKNET 4800DPI Wireless Vertical Mouse
The TECKNET Wireless Vertical Mouse offers a remarkable combination of features designed for user comfort and efficiency. With adjustable DPI levels up to 4800, you can tailor cursor speed to suit your tasks, whether you're gaming or working on design projects. Its ergonomic vertical design ensures that your wrist remains in a natural position, reducing fatigue during long usage. Additionally, the quieter click technology minimises noise, making it ideal for quiet environments like libraries or offices. Finally, its energy-efficient design prolongs battery life, allowing you to focus on your work without interruptions.
ProtoArc EM11 NL Wireless Ergonomic Mouse
The ProtoArc EM11 NL Mouse is designed for comfort and convenience. Its ergonomic shape, featuring an extended wrist rest, supports a natural hand position, helping to reduce strain during long hours of use. You can connect it to three devices simultaneously, making it easy to switch between your computer, tablet, and more. With a rechargeable battery, you won’t have to worry about running out of power, and the automatic sleep mode saves energy when not in use. The adjustable DPI settings allow for precise tracking, enhancing your browsing experience.
Anker Ergonomic Vertical USB Wired Mouse
The Anker Vertical Mouse features a scientific ergonomic design that promotes a healthy "handshake" position, helping to reduce strain during prolonged use. With a DPI resolution of 1000/1600, it offers enhanced sensitivity for smooth and precise tracking on various surfaces. The added next and previous buttons make browsing webpages easier, perfect for internet users and gamers alike. Its generous 1.5m USB cable allows for comfortable movement, giving you the freedom to work or play without feeling restricted.
Logitech MX Vertical Ergonomic Wireless Mouse
The Logitech MX Vertical Mouse is designed to enhance your comfort during extended computer use. Its natural handshake position reduces muscular effort by 10%, promoting a more relaxed grip. The 57-degree vertical angle improves wrist posture, alleviating pressure and ensuring your thumb rests comfortably. With advanced 4000 DPI optical tracking, you'll experience less hand movement and reduced fatigue, while a simple button press allows you to adjust cursor speed for precision tasks.
TECKNET Ergonomic Wireless Rechargeable Mouse
The TECKNET Ergonomic Mouse offers a natural hand position for maximum comfort, reducing wrist tension during use. Its rechargeable feature allows you to enjoy up to 60 days of usage on a single charge, eliminating the hassle of frequent charging. You can continue using the mouse while it's charging, which adds to your convenience. With its advanced 2.4 GHz wireless technology, you can expect a stable connection up to 10 metres, making it ideal for your laptop or PC.
TECKNET Wireless Vertical Ergonomic Mouse
The TECKNET Vertical Mouse offers a seamless experience with its ability to connect to three devices through Bluetooth and 2.4GHz USB modes. This feature allows you to switch effortlessly between devices, saving valuable USB ports. With six adjustable DPI levels, you can tailor the sensitivity to your liking, ensuring smooth operation on various surfaces. Its silent clicking mechanism is perfect for quiet environments, allowing you to work or study without disturbing others. The ergonomic design promotes comfort by reducing wrist strain during prolonged use.
Trust Verto Ergonomic Vertical Mouse with LED
The Trust Verto Mouse is designed to combat strain and discomfort during use. Its ergonomic shape positions your arm and wrist at a natural 60°, allowing you to work effortlessly. You will feel the difference with its lightweight design and comfortable thumb rest, providing a secure grip for all hand sizes. The accurate 1000/1600 DPI optical sensor, along with two thumb buttons, ensures that you have precise control over your tasks. Plus, the plug-and-play feature means you can connect it easily and start working right away.
Trust Verto Wireless Ergonomic Vertical Mouse
The Trust Verto Mouse is designed to reduce strain and discomfort while you work. Its ergonomic shape positions your arm and wrist at a natural 60°, making it easier for you to work for longer periods without pain. The lightweight design fits all hand sizes, offering a thumb rest and a rubber coating for improved grip and comfort. With a wireless range of 10 metres, you can enjoy greater freedom of movement, allowing you to maintain better posture while you work.
Frequently Asked Questions (FAQs)
1. Are ergonomic mice really better?
Based on our research and the research of others, ergonomic mice that promote a more upright hand and wrist posture (like a handshake) better match our complex anatomy and can put less strain on our muscles. An ergonomic mouse can play an important role in promoting comfort.”
2. What type of mouse is ergonomic?
Ergonomically, the trackball finger mouse exerts very little strain on the wrists. This makes it an excellent alternative for people with arthritis or CTS.
3. Are vertical mice Really ergonomic?
A vertical mouse is ergonomically shaped to help the user maintain that handshake design while operating it. Instead of twisting your wrist so it's parallel to the desk to operate a regular mouse, there is little to no twisting of the wrist required to grasp a vertical mouse.
4. Are ergonomic gaming mice worth it?
Ergonomics. Gaming mice are often more comfortable than regular mice as they are designed for longer periods of gaming in mind. Different gaming mice will support specific grip styles, will have ambidextrous support or will be ergonomic for one hand, and some mice have adjustable weight.
During our ergonomic mice research, we found 306 ergonomic mice products and shortlisted 10 quality products. We collected and analyzed 481,814 customer reviews through our big data system to write the ergonomic mice list. We found that most customers choose ergonomic mice with an average price of £17.75.
The ergonomic mice are available for purchase. We have researched hundreds of brands and picked the top brands of ergonomic mice, including Anker, Logitech, TECKNET, ProtoArc, Trust. The seller of top 1 product has received honest feedback from 14,997 consumers with an average rating of 4.9.

Kenneth Collin graduated from Imperial College, London, at 22. He is a UX/UI designer, a web developer, and a writer, amongst others. At age 14, Kenneth programmed his first app. Kenneth's app served as a remote control for censored devices. "When I was 8, I would pick up scraps from electronics and try to rebuild or at least fix them," Kenneth said in one of his recent articles on Home repairs for top gadgets.