Best Face Spot Treatment Serums of 2026

Name: LANBENA Acne Spot Serum for Overnight Treatment
Brand: LANBENA

Charlotte Powell

Last Updated: 2 Feb 2026

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Face Spot Treatment Serums are skincare products designed to target specific areas of the face affected by blemishes and dark spots. These serums are formulated with powerful ingredients that work to reduce the appearance of hyperpigmentation, acne scars, and other skin imperfections. They are easy to apply and can be used as part of your daily skincare routine. Face Spot Treatment Serums are ideal for those looking to improve the overall appearance of their skin and achieve a more even complexion.

At a Glance: Our Top Picks

#TOP 1

LANBENA Acne Spot Serum for Overnight Treatment

9.8

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LANBENA Acne Spot Serum for Overnight Treatment

#TOP1

9.8

Read Review

#TOP 2

12% Acid Serum Facial Cream

9.7

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12% Acid Serum Facial Cream

#TOP2

9.7

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#TOP 3

Anti Acne Face Serum - Salicylic Acid Drying Lotion

9.5

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Anti Acne Face Serum - Salicylic Acid Drying Lotion

#TOP3

9.5

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Top 10 Face Spot Treatment Serums

#TOP 1 Best Acne Face Spot Treatment

LANBENA Acne Spot Serum for Overnight Treatment

LANBENA

Off White

11.9 ml (Pack of 1)

LANBENA Precision Acne Treatment Spot Serum, Drying Lotion, Overnight Acne Treatment For Face, Dry Out Pimples, Blemishes, Zits And Clean Pores, 0.42 Fl Oz (Pack of 1)

9.8

FTB Score

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The LANBENA Acne Spot Serum is designed to provide rapid relief from pesky pimples while you sleep. It effectively reduces the size and severity of breakouts, helping to prevent acne scars and keep your skin smooth. This serum targets cystic acne and blemishes by unclogging pores and removing oil buildup, ensuring your skin stays clean. It is gentle enough for sensitive skin, making it a safe choice for those prone to irritation.

What We Like

Fast-acting results overnight

Targets cystic acne effectively

Safe for sensitive skin

Prevents new breakouts

#TOP 2

12% Acid Serum Facial Cream

ISBEAUSOLS

20 g (Pack of 1)

12% Acid Serum Facial Cream,Face Spot Treatment Serum Cream,Acne Treatment Creams for Reduces Acne & Soothes Redness,Skin Care Pimple Creams with Salicylic Acid&Niacinamide,Suitable for All Skin Types

9.7

FTB Score

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Features

[Targeted Anti-Acne Formula] Our 12% Acid Acne Treatment Cream Is Specifically Designed To Fight Acne And Prevent Breakouts.The Potent Blend Of 12% Acid And Salicylic Acid Penetrates Deep Into Pores To Tackle The Root Causes Of Acne, Reduce Visible Blemishes, And Stop New Spots From Forming.A Must-Have For Clearer, Healthier-Looking Skin.

[12% Acid Power Cream] Formulated With A High-Strength 12% Acid, This 12% Acid Facial Serum Cream Helps Soothe Redness, Fade Dark Spots, And Clear Acne And Blemishes.Our Face Serum Cream Works To Unclog Pores, Reduce Inflammation, And Restore Calm, Nourished Skin — Making It Ideal For Troubled And Sensitive Skin Types.

[Refines Texture & Balances Oil] With Its Lightweight, Non-Greasy Texture, The Acid 12% Facial Serum Cream Absorbs Quickly Without Clogging Pores.It Helps Control Excess Sebum, Clear Out Pore Impurities, And Smooth Rough Skin Texture.Perfect For Oily And Acne-Prone Skin, Leaving Your Complexion Softer, Clearer, And More Refined.

[Calming & Restorative] Infused With Natural Soothing Ingredients, This Face Spot Treatment Cream Is Ideal For Sensitive, Irritated, Or Reactive Skin.This 12% Acid Acne Treatment Cream For Face Delivers Instant Relief From Redness, Calms Skin, And Supports The Skin's Natural Recovery Process — All While Keeping Your Complexion Hydrated And Balanced.

[A Thoughtful Gift For Clearer Skin] Beautifully Packaged And Highly Effective, This Cream Makes A Meaningful Gift For Anyone Struggling With Acne Or Redness.Ideal For Birthdays, Holidays, Or Self-Care Moments — A Gentle Yet Powerful Way To Show You Care For Their Skin And Confidence.

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#TOP 3

Anti Acne Face Serum - Salicylic Acid Drying Lotion

ISBEAUSOLS

29 ml (Pack of 1)

Anti Acne Face Serum - Salicylic Acid Drying Lotion - Overnight Acne Drying Lotion - Anti Acne Serum Dry Out Blemishes & Pimple Reduce Redness - Pimple Lotion - Spot Treatment for All Skin Types

9.5

FTB Score

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Features

[Salicylic Acid For Deep Cleansing] This Acne Drying Lotion Features Salicylic Acid, Known For Its Ability To Penetrate Deep Into Pores. It Effectively Exfoliates Dead Skin Cells, Dissolves Excess Oil, And Unclogs Pores, Preventing Future Breakouts And Promoting A Healthier Complexion.

[Overnight Acne Treatment] The Salicylic Acid Drying Lotion Is Designed To Work While You Sleep, Delivering Powerful Results By Morning. It Targets Active Breakouts, Including Whiteheads, Blackheads, And Pimples, Reducing Their Size And Redness. Wake Up To Visibly Clearer And Smoother Skin.

[Gentle Yet Effective Formula] Unlike Harsh Acne Treatments That Can Irritate Or Over-Dry The Skin, This Anti Acne Serum Is Formulated To Be Gentle Yet Effective. It Dries Out Blemishes Without Stripping The Skin Of Its Natural Moisture, Making It Suitable For Daily Use On All Skin Types, Including Sensitive Skin.

[Easy To Use And Travel-Friendly] The Overnight Acne Drying Lotion Comes In A Convenient Bottle, Allowing You To Apply It Easily To Affected Areas Without Wasting Product. Its Compact Size Makes It Perfect For On-The-Go Use, Ensuring You Can Tackle Breakouts Anytime, Anywhere.

[Calming And Soothing Formula] In Addition To Salicylic Acid, This Pimple Lotion Contains Calming And Soothing Ingredients. These Components Help Reduce Irritation And Redness, Making It Suitable For Sensitive Skin While Still Targeting Acne Effectively Without Over-Drying.

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#TOP 4

Super Facialist Breakout Buster Serum

Super Facialist

BA-SF26161

30 milliliters

Super Facialist Breakout Buster Serum Cover

Super Facialist Breakout Buster Serum - Clear Skin Solutions, Spot Treatment for Acne with 10% Niacinamide, Tea Tree Oil & Prebiotics, Vegan Friendly 30ml

9.5

FTB Score

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Features

10% NIACINAMIDE: Dermatologically Tested Serum With Vitamin B 3 Helps Reduce The Appearance Of Oily Skin, Minimise Redness & Works As A Great Acne Treatment

SERUM: This Spot Treatment Serum With Super Facialist Skin Balancing Complex Helps Improve Hydration, Minimise Skin Dryness & Boost Skin Barrier Function - Effective Face Care

TEA TREE OIL: Organic Tea Tree Is Antimicrobial To Help Minimise The Appearance Of Breakouts & Gives This. Serum A Fresh Scent

SKINCARE SET: Pair This Spot Treatment Serum With Super Facialist Clear Skin Daily Moisturiser & Upgrade Your Skincare Routine - Makes A Fabulous Gift Set Idea

PREBIOTICS: Prebiotics From Chicory Are Added To This Face Cream To Keep Your Skin Balanced & Prevent Spots - Gentle Skincare

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#TOP 5

Drying Lotion for Acne - Salicylic Acid Acne Treatment

Cureluxe

29 ml (Pack of 1)

Drying Lotion for Acne - Salicylic Acid Acne Treatment Cover

Drying Lotion for Acne - Salicylic Acid Acne Treatment - Anti Acne Face Serum - Overnight Drying Lotion for Spot Treatment - Acne Removing Essence Powder - Dry Out Blemishes & Pimple, Reduce Redness

9.5

FTB Score

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Features

[ Kind To Skin, Tough On Breakouts] Crafted For All Skin Types—including Sensitive—this Anti Acne Face Serum Balances Strength And Gentleness. Our Spot Remover Lotion Effectively Dries Out Blemishes Without Causing Peeling, Flaking, Or Dehydration, Making It Ideal For Everyday Use In Your Acne-Fighting Skincare Routine.

[ Nightly Blemish Repair For Clearer Skin By Morning] This Targeted Salicylic Acid Drying Lotion Works While You Sleep To Visibly Reduce The Size And Redness Of Active Blemishes. Whether You're Dealing With Whiteheads, Blackheads, Or Deep Under-The-Skin Pimples,our Drying Lotion For Acne Speeds Up The Healing Cycle Overnight, So You Wake Up With A Fresher, More Refined Complexion.

[ Compact, Targeted, And Effortless Application] Designed For Targeted Spot Treatment, The Precision Bottle Dispenses Just The Right Amount Without Mess Or Waste. Its Travel-Ready Size Makes It The Perfect Companion For Skincare Emergencies At Home, On The Road, Or After The Gym — Wherever Breakouts Strike.

[ Soothes While It Works] This Fast-Acting Acne Solution Does More Than Treat Spots — It Calms Irritated Skin With Anti-Inflammatory Ingredients That Comfort And Rebalance. Redness Is Visibly Reduced, Inflammation Subsides, And The Skin Barrier Stays Protected, Even In Reactive Or Blemish-Prone Areas.

[Deep-Cleansing Pore Power With Salicylic Acid] Formulated With A Potent Dose Of Salicylic Acid, This Acne Treatment Lotion Penetrates Deep Into Pores To Loosen Buildup, Clear Congestion, And Dissolve Oil. Our Salicylic Acid Serum Promotes Smoother Skin Texture While Actively Preventing Future Breakouts From Forming Beneath The Surface.

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#TOP 6

12% Acid Spot Cream - Acne Cream

NLFOX

12% Acid Spot Cream - Acne Cream for Face - Facial acne Scar Treatment - Pimple cream Face Moisturiser - Facial Serum Skin Care Faded Dark Spots, Blackhead, Redness, Even Skin Tone

9.3

FTB Score

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Features

[Balance Oil & Unclog Pores] :Acid 12% Spot Cream Easily Helps You Balance Excess Sebum, Reduce Pore Dirt, Evenly Distribute Skin Texture & Make The Skin Smoother & More Elastic

[12% Acid Serum] :The Acid Acne Cream Helps Alleviate Facial Redness And Reduce The Occurrence Of Blemishes, Pimples & Acne. Enjoy A More Relaxed Way To Fade Past Acne, Unclog Pores And Nourish The Skin

[More Delicate Skin] :This Acne Scar Treatment Balances Oil Production And Deeply Hydrates The Skin, Ensuring A Matte, Refreshed Look Without Excess Shine. Regular Use Can Help Maintain A Balanced And Hydrated Complexion

[Gentle On Skin] :Formulated With Mild Ingredients, Thisacne Cream For Face Is Safe For All Skin, Providing Nourishment Without Harsh Chemicals. Ideal For All Skin Type, This Formula Works To Enhance Skin Appearance Over Time

[Daily Skin Care] : This Lightweight Pimple Cream Absorbs Quickly, Making It A Seamless Addition To Any Skincare Routine. Apply It Effortlessly In The Morning And Evening For Consistent Results Without Any Heavy Or Greasy Residue

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#TOP 7

Eucerin Anti-Pigment Spot Corrector 5 ml

Eucerin

4005800213113

no Colour

5 g (Pack of 1)

Eucerin Anti-Pigment Spot Corrector 5 ml Cover

Eucerin Anti-Pigment Spot Corrector 5 ml, Dark Spot Correcting Serum, Hyperpigmentation Treatment, Evens Skin Tone, Non-Greasy Serum for Face, Suitable for All Skin Types

9.3

FTB Score

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Features

Eucerin Anti-Pigment — The Eucerin Anti-Pigment Products Are Specially Formulated To Target Hyperpigmentation, Dark Spots, And Uneven Skin Tone For A Brighter And Glowing Complexion

Targeted Dark Spot Treatment — This Face Serum For Women Effectively Reduces Dark Spots And Prevents Their Re-Appearance By Treating The Root Cause Of Hyperpigmentation, Promoting A More Even Skin Tone

Scope Of Delivery — Eucerin Anti-Pigment Spot Corrector, Dark Spot Serum For Face, Suitable For All Skin Types, Unperfumed Formula, Dermatologically Tested, 1x 5ml, Article Nr: 83507

Precision Application — The Non-Greasy Gel Formula Comes With A Topical Applicator, Allowing For Easy And Precise Application To Small Areas Of Hyperpigmentation, Making It An Ideal Spot Treatment

Innovative Formula — This Dark Spot Serum Contains Thiamidol, An Effective And Patented Ingredient That Reduces Melanin Production, Visibly Diminishing Dark Patches And Age Spots With Continuous Use

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#TOP 8

Precision Acne Treatment Spot Serum

INSKIN

Precision Acne Treatment Spot Serum, Overnight Drying Lotion, Anti Acne Serum,Spot Treatment, Pimple Lotion for Redness,Dry Out Blemishes & Pimple, Acnecide Face Lotio-n for Women Men

9.2

FTB Score

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Features

[Deep Pore Cleansing – Stop Acne At The Source] This Acne-Fighting Serum Unclogs Pores By Dissolving Oil, Dirt, And Debris—the Root Cause Of Breakouts. Whether You Struggle With Hormonal Acne, Blackheads, Or Stubborn Pimples, Our Pore-Refining Formula Penetrates Deep To Heal Active Acne And Prevent Future Flare-Ups. Ideal For Oily And Combination Skin!

[Fast-Acting Acne Treatment – Overnight Results] Get Clearer Skin Fast With Our Drying Lotion For Acne! Designed To Reduce Pimples Overnight, This Powerful Acne Spot Treatment Shrinks Breakouts, Minimizes Redness, And Prevents Acne Scars. Perfect For Cystic Acne, Whiteheads, And Blemishes, It Works While You Sleep, Leaving Skin Smoother By Morning. No Harsh Chemicals—just Visible Results!

[Overnight Acne Solution – Wake Up To Calm Skin] Apply Before Bed And Let This Acne Drying Lotion Work Its Magic! The Exfoliating And Healing Formula Targets Pimples, Cysts, And Redness, Smoothing Skin Texture By Morning. No Greasy Residue—just Fast Acne Relief And A Blemish-Free Complexion In Days!

[Gentle Yet Effective – Safe For Sensitive Skin] Unlike Harsh Acne Treatments, Our Hypoallergenic Formula Soothes Irritation While Fighting Breakouts. Our Spot Drying Lotion Is Perfect For Delicate, Acne-Prone Skin. Reduces Swelling Overnight Without Dryness Or Peeling—get Clear Skin Without The Sting!

[Cruelty-Free & Vegan – Clean Skincare You Can Trust] Vegan And Cruelty-Free, Our Acne Treatment Contains Plant-Based Ingredients With A Mild, Natural Scent. No Animal Testing, No Harmful Additives—just Safe, Effective Acne Care For All Skin Types. Hypoallergenic, Non-Comedogenic!

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#TOP 9

Dark Spot Correcting Glow Serum & Spot Cream

Epiregn

Dark Spot Correcting Glow Serum & Spot Cream, Dark Spot Remover for Face, Pigmentation Removal Cream & Acne Cream, Hyperpigmentation Treatment with Niacinamide, Age Spot Corrector & Face Moisturiser

9.1

FTB Score

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Features

Deep Hydration & Nourishment: Enriched With Niacinamide And Botanical Extracts, This Pigmentation Removal Cream Keeps Skin Hydrated, Nourished, And Plump. The Lightweight Face Cream Absorbs Quickly, Acting As A Moisturiser For Dry Skin Without Greasiness

Dual-Action Dark Spot Care: This 2pcs Set Combines A Dark Spot Correcting Glow Serum And Glow Cream, Working Together As A Dark Spot Corrector To Target Pigmentation, Acne Scars, And Age Spots. Ideal As A Spot Cream Or Acne Cream For Clearer, Smoother-Looking Skin

Multi-Purpose Use: Designed For Face, Neck, Hands, And Décolletage, This Age Spot Remover For Face And Pigmentation Treatment Adapts To Different Needs. Whether For Acne Marks, Dark Spots, Or Uneven Tone, It Supports Overall Skincare And Face Care

Gentle Yet Effective Formula: This Hyperpigmentation Cream And Acne Treatment Set Is Crafted With Skin-Friendly Ingredients Suitable For All Skin Types. Free From Harsh Additives, It Offers Safe Spot Treatment Without Causing Dryness Or Irritation

Brigh-Ten & Smooth Complexion: Formulated As A Hyperpigmentation Treatment, The Serum And Cream Duo Reduces Visible Spots And Dullness, Leaving Skin More Even-Toned And Radiant. Perfect For Daily Face Care, Helping Restore Your Skin's Natural Glow

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#TOP 10

Drying Lotion for Acne Treatment

MEITREND

1 ml (Pack of 1)

Drying Lotion for Acne Treatment,Anti Acne Face Serum,Overnight Acne Drying Lotion,Spot Treatment,Pimple Lotio-n,Dry Out Blemishes & Pimple Reduce Redness

9.1

FTB Score

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Features

[Overnight Acne Drying Lotion] This Drying Lotion For Acne Is Formulated To Work Overnight.Simply Apply A Small Amount To Blemishes Before Bed, And By Morning, You'll Notice Reduced Redness. Its Fast-Acting Ingredients Start Working Immediately, Drying Out Pimples And Helping Your Skin Recover Quickly.

[Drying Lotion For Acne Treatment] Look Your Best As An Overnight Success From Our Drying Lotion!Our Drying Lotion Is Specifically Formulated To Combat Stubborn Acne, Including Whiteheads, Blackheads, Spots And Pimples.Its Powerful Yet Gentle Formula Penetrates Deep Into Pores To Soothe And Dry Out Blemishes For Clearer, Smoother Skin.

[Travel Size & Easy To Carry] The Acne Treatment Lotion Comes In A Convenient Bottle, Allowing You To Apply It Easily To Affected Areas Without Wasting Product. As A Daily Care & Skin Barrier Maintenance, It Can Reduce The Appearance Of Facial Spots.It Is A Good Daily Skin Care Product For You!

[Spot Treatment For All Skin Parts] Perfect For All Around Treatment Of Face And Body Acne. Directly Apply Lotion On The Affected Areas To Calm Tender Breakouts And Rinse Off In The Morning.Great As A Spot Treatment.

[Dry Out Blemishes & Pimple] Its Powerful Yet Gentle Formula Penetrates Deep Into Pores To Unclog Impurities, Reduce Redness, And Promote Clearer Skin. It Works Effectively To Dry Out Existing Blemishes While Preventing New Ones From Forming.

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Frequently Asked Questions (FAQs)

1. Is serum good for pimple marks?

Serums can help lighten the appearance of scars caused by acne over time. You must look out for scar-repelling ingredients in the next serum you buy - vitamin C, niacinamide, salicylic acid, lactic acid, vitamin E, and rosehip oil are a few agents that work toward lightening your scars.

Editor's Notes

During our face spot treatment serum research, we found 73 face spot treatment serum products and shortlisted 10 quality products. We collected and analyzed 1,754 customer reviews through our big data system to write the face spot treatment serums list. We found that most customers choose face spot treatment serums with an average price of £20.00.

The face spot treatment serums are available for purchase. We have researched hundreds of brands and picked the top brands of face spot treatment serums, including LANBENA, ISBEAUSOLS, Super Facialist, Cureluxe, NLFOX.

Written by

Charlotte Powell

Charlotte Powell is a dermatologist and a licensed cosmetologist from Westminster, London. However, she was first a cosmetologist from London Beauty Training School. According to Charlotte, she needed better insight into the human skin, hence the dermatology degree. Long before she acquired her degree, she wrote and edited articles, eBooks, and editorials for companies and websites. Charlotte combines her skill and knowledge in providing DIY Beauty tips amongst other fashion related topics.