Best Lotion Face Spot Treatments of 2026

Name: LANBENA Acne Spot Serum for Overnight Treatment
Brand: LANBENA

Charlotte Powell

Last Updated: 2 Feb 2026

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Lotion face spot treatments are topical skincare products designed to target and reduce the appearance of blemishes, acne, and dark spots on the face. These products often contain active ingredients such as salicylic acid, benzoyl peroxide, or glycolic acid, which work to exfoliate and unclog pores, reduce inflammation, and promote cell turnover. Lotion face spot treatments are a popular addition to many people's skincare routines, particularly those with oily or acne-prone skin. They can be used as a spot treatment on individual blemishes or applied to larger areas of the face to prevent breakouts and promote overall skin health.

At a Glance: Our Top Picks

#TOP 1

LANBENA Acne Spot Serum for Overnight Treatment

9.8

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LANBENA Acne Spot Serum for Overnight Treatment

#TOP1

9.8

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#TOP 2

Anti Acne Face Serum - Salicylic Acid Drying Lotion

9.7

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Anti Acne Face Serum - Salicylic Acid Drying Lotion

#TOP2

9.7

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#TOP 3

Drying Lotion for Acne - Salicylic Acid Acne Treatment

9.5

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Drying Lotion for Acne - Salicylic Acid Acne Treatment

#TOP3

9.5

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Top 10 Lotion Face Spot Treatments

#TOP 1 Best Acne Face Spot Treatment

LANBENA Acne Spot Serum for Overnight Treatment

LANBENA

Off White

11.9 ml (Pack of 1)

LANBENA Precision Acne Treatment Spot Serum, Drying Lotion, Overnight Acne Treatment For Face, Dry Out Pimples, Blemishes, Zits And Clean Pores, 0.42 Fl Oz (Pack of 1)

9.8

FTB Score

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The LANBENA Acne Spot Serum is designed to provide rapid relief from pesky pimples while you sleep. It effectively reduces the size and severity of breakouts, helping to prevent acne scars and keep your skin smooth. This serum targets cystic acne and blemishes by unclogging pores and removing oil buildup, ensuring your skin stays clean. It is gentle enough for sensitive skin, making it a safe choice for those prone to irritation.

What We Like

Fast-acting results overnight

Targets cystic acne effectively

Safe for sensitive skin

Prevents new breakouts

#TOP 2

Anti Acne Face Serum - Salicylic Acid Drying Lotion

ISBEAUSOLS

29 ml (Pack of 1)

Anti Acne Face Serum - Salicylic Acid Drying Lotion - Overnight Acne Drying Lotion - Anti Acne Serum Dry Out Blemishes & Pimple Reduce Redness - Pimple Lotion - Spot Treatment for All Skin Types

9.7

FTB Score

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Features

[Salicylic Acid For Deep Cleansing] This Acne Drying Lotion Features Salicylic Acid, Known For Its Ability To Penetrate Deep Into Pores. It Effectively Exfoliates Dead Skin Cells, Dissolves Excess Oil, And Unclogs Pores, Preventing Future Breakouts And Promoting A Healthier Complexion.

[Overnight Acne Treatment] The Salicylic Acid Drying Lotion Is Designed To Work While You Sleep, Delivering Powerful Results By Morning. It Targets Active Breakouts, Including Whiteheads, Blackheads, And Pimples, Reducing Their Size And Redness. Wake Up To Visibly Clearer And Smoother Skin.

[Gentle Yet Effective Formula] Unlike Harsh Acne Treatments That Can Irritate Or Over-Dry The Skin, This Anti Acne Serum Is Formulated To Be Gentle Yet Effective. It Dries Out Blemishes Without Stripping The Skin Of Its Natural Moisture, Making It Suitable For Daily Use On All Skin Types, Including Sensitive Skin.

[Easy To Use And Travel-Friendly] The Overnight Acne Drying Lotion Comes In A Convenient Bottle, Allowing You To Apply It Easily To Affected Areas Without Wasting Product. Its Compact Size Makes It Perfect For On-The-Go Use, Ensuring You Can Tackle Breakouts Anytime, Anywhere.

[Calming And Soothing Formula] In Addition To Salicylic Acid, This Pimple Lotion Contains Calming And Soothing Ingredients. These Components Help Reduce Irritation And Redness, Making It Suitable For Sensitive Skin While Still Targeting Acne Effectively Without Over-Drying.

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#TOP 3

Drying Lotion for Acne - Salicylic Acid Acne Treatment

Cureluxe

29 ml (Pack of 1)

Drying Lotion for Acne - Salicylic Acid Acne Treatment - Anti Acne Face Serum - Overnight Drying Lotion for Spot Treatment - Acne Removing Essence Powder - Dry Out Blemishes & Pimple, Reduce Redness

9.5

FTB Score

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Features

[ Kind To Skin, Tough On Breakouts] Crafted For All Skin Types—including Sensitive—this Anti Acne Face Serum Balances Strength And Gentleness. Our Spot Remover Lotion Effectively Dries Out Blemishes Without Causing Peeling, Flaking, Or Dehydration, Making It Ideal For Everyday Use In Your Acne-Fighting Skincare Routine.

[ Nightly Blemish Repair For Clearer Skin By Morning] This Targeted Salicylic Acid Drying Lotion Works While You Sleep To Visibly Reduce The Size And Redness Of Active Blemishes. Whether You're Dealing With Whiteheads, Blackheads, Or Deep Under-The-Skin Pimples,our Drying Lotion For Acne Speeds Up The Healing Cycle Overnight, So You Wake Up With A Fresher, More Refined Complexion.

[ Compact, Targeted, And Effortless Application] Designed For Targeted Spot Treatment, The Precision Bottle Dispenses Just The Right Amount Without Mess Or Waste. Its Travel-Ready Size Makes It The Perfect Companion For Skincare Emergencies At Home, On The Road, Or After The Gym — Wherever Breakouts Strike.

[ Soothes While It Works] This Fast-Acting Acne Solution Does More Than Treat Spots — It Calms Irritated Skin With Anti-Inflammatory Ingredients That Comfort And Rebalance. Redness Is Visibly Reduced, Inflammation Subsides, And The Skin Barrier Stays Protected, Even In Reactive Or Blemish-Prone Areas.

[Deep-Cleansing Pore Power With Salicylic Acid] Formulated With A Potent Dose Of Salicylic Acid, This Acne Treatment Lotion Penetrates Deep Into Pores To Loosen Buildup, Clear Congestion, And Dissolve Oil. Our Salicylic Acid Serum Promotes Smoother Skin Texture While Actively Preventing Future Breakouts From Forming Beneath The Surface.

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#TOP 4

T-Zone Salicylic Acid & Tea Tree Overnight Blemish Solution 30ml - Fast-Acting Drying Lotion

T-Zone

ZN2015

White

T-Zone Salicylic Acid & Tea Tree Overnight Blemish Solution 30ml - Fast-Acting Drying Lotion Cover

T-Zone Salicylic Acid & Tea Tree Overnight Blemish Solution 30ml - Fast-Acting Drying Lotion for Targeted Spot Treatment, Clears Blemishes Overnight & Helps Prevent Future Breakouts

9.5

FTB Score

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Features

POWERED BY SALICYLIC ACID: Formulated With Salicylic Acid To Penetrate Deep Into Pores, Gently Exfoliate And Dry Out Blemishes, Helping To Clear Skin From Within.

FAST-ACTING OVERNIGHT DRYING LOTION: A Targeted Treatment That Works While You Sleep To Visibly Reduce The Appearance Of Blemishes And Redness By Morning, Promoting A Clearer Complexion.

TEA TREE & ZINC PURIFYING COMPLEX: Enriched With Antibacterial Tea Tree Oil And Oil-Balancing Zinc To Help Calm Irritation, Regulate Excess Sebum And Prevent Future Breakouts.

TARGETED APPLICATION FOR TROUBLED SKIN: Dual-Phase Formula Separates Naturally — Simply Dip A Cotton Bud Into The Pink Layer And Apply Directly To Blemishes For Instant Action.

CLEARER SKIN OVERNIGHT: Designed For Blemish-Prone And Oily Skin Types, This Fast-Working Solution Helps Dry Out Spots And Support A Smoother, More Balanced Complexion With Consistent Use.

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#TOP 5

Precision Acne Treatment Spot Serum, Overnight Drying Lotion

INSKIN

Precision Acne Treatment Spot Serum, Overnight Drying Lotion, Anti Acne Serum,Spot Treatment, Pimple Lotion for Redness,Dry Out Blemishes & Pimple, Acnecide Face Lotio-n for Women Men

9.3

FTB Score

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Features

[Deep Pore Cleansing – Stop Acne At The Source] This Acne-Fighting Serum Unclogs Pores By Dissolving Oil, Dirt, And Debris—the Root Cause Of Breakouts. Whether You Struggle With Hormonal Acne, Blackheads, Or Stubborn Pimples, Our Pore-Refining Formula Penetrates Deep To Heal Active Acne And Prevent Future Flare-Ups. Ideal For Oily And Combination Skin!

[Fast-Acting Acne Treatment – Overnight Results] Get Clearer Skin Fast With Our Drying Lotion For Acne! Designed To Reduce Pimples Overnight, This Powerful Acne Spot Treatment Shrinks Breakouts, Minimizes Redness, And Prevents Acne Scars. Perfect For Cystic Acne, Whiteheads, And Blemishes, It Works While You Sleep, Leaving Skin Smoother By Morning. No Harsh Chemicals—just Visible Results!

[Overnight Acne Solution – Wake Up To Calm Skin] Apply Before Bed And Let This Acne Drying Lotion Work Its Magic! The Exfoliating And Healing Formula Targets Pimples, Cysts, And Redness, Smoothing Skin Texture By Morning. No Greasy Residue—just Fast Acne Relief And A Blemish-Free Complexion In Days!

[Gentle Yet Effective – Safe For Sensitive Skin] Unlike Harsh Acne Treatments, Our Hypoallergenic Formula Soothes Irritation While Fighting Breakouts. Our Spot Drying Lotion Is Perfect For Delicate, Acne-Prone Skin. Reduces Swelling Overnight Without Dryness Or Peeling—get Clear Skin Without The Sting!

[Cruelty-Free & Vegan – Clean Skincare You Can Trust] Vegan And Cruelty-Free, Our Acne Treatment Contains Plant-Based Ingredients With A Mild, Natural Scent. No Animal Testing, No Harmful Additives—just Safe, Effective Acne Care For All Skin Types. Hypoallergenic, Non-Comedogenic!

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#TOP 6

Drying Lotion for Acne Spots

Trendyfave

29 ml (Pack of 1)

Drying Lotion for Acne Spots - Overnight Drying Lotion Acne Treatment - Anti Acne Face Serum Dry Out Blemishes & Pimple Reduce Redness - Pink Spot Treatment for All Skin Types, 29ml

9.2

FTB Score

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Features

[Targeted Care For Pimples And Blemishes] This Fast-Acting Acne Drying Lotion Is Ideal For Blemish-Prone Skin. It Works As A Pimple Drying Lotion, Targeting Individual Spots By Absorbing Oil And Soothing Inflammation. Perfect For Whiteheads, Clogged Pores Or Active Breakouts, It Helps Improve Skin Clarity With Precision Application.

[Overnight Spot Care, Wake Up To Clearer Skin] This Acne Spot Treatment For Face Is Designed For Overnight Use To Visibly Reduce Redness And Calm Irritation. With Asalicy-Lic Acid Serum Base, It Penetrates Pores, Absorbs Excess Oil And Dries Out Blemishes While You Sleep. Wake Up To Smoother, Clearer-Looking Skin With Less Visible Breakouts.

[Portable Pink Bottle, Quick Spot Application Anytime] This Compact Pink Pimple Drying Lotion (29ml) Fits Easily Into Your Makeup Bag For On-The-Go Blemish Care. No Shaking Needed—dip A Cotton Swab To Reach The Pink Sediment And Apply Directly To Spots. Ideal For Travel, Commutes Or Late Nights, Also Works As An Easy Back Acne Treatment.

[Gentle & Suitable For Sensitive Skin] Unlike Harsh Treatments, This Acne Lotion For Face Helps Calm Visible Redness Without Overdrying. Enriched With Plant Extracts, The Non-Stripping Formula Soothes Irritated Skin. As Asalicy-Lic Acid Moisturiser, It's Alcohol-Free And Fragrance-Free—ideal For Spot Use Even On Sensitive Skin Types.

[Deep Clean Pores, Help Prevent Breakouts] Formulated To Remove Buildup And Dead Skin, This Lotion Acts As A Spot Treatment For Face And Helps Reduce Pore Congestion. Used Regularly, This Effective Spot Acne Treatment Supports Smoother Skin Texture And Helps Minimise The Appearance Of Future Breakouts, Promoting A Fresh, Healthy Look.

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#TOP 7

Drying Lotion for Acne Treatment

MEITREND

1 ml (Pack of 1)

Drying Lotion for Acne Treatment,Anti Acne Face Serum,Overnight Acne Drying Lotion,Spot Treatment,Pimple Lotio-n,Dry Out Blemishes & Pimple Reduce Redness

9.2

FTB Score

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Features

[Overnight Acne Drying Lotion] This Drying Lotion For Acne Is Formulated To Work Overnight.Simply Apply A Small Amount To Blemishes Before Bed, And By Morning, You'll Notice Reduced Redness. Its Fast-Acting Ingredients Start Working Immediately, Drying Out Pimples And Helping Your Skin Recover Quickly.

[Drying Lotion For Acne Treatment] Look Your Best As An Overnight Success From Our Drying Lotion!Our Drying Lotion Is Specifically Formulated To Combat Stubborn Acne, Including Whiteheads, Blackheads, Spots And Pimples.Its Powerful Yet Gentle Formula Penetrates Deep Into Pores To Soothe And Dry Out Blemishes For Clearer, Smoother Skin.

[Travel Size & Easy To Carry] The Acne Treatment Lotion Comes In A Convenient Bottle, Allowing You To Apply It Easily To Affected Areas Without Wasting Product. As A Daily Care & Skin Barrier Maintenance, It Can Reduce The Appearance Of Facial Spots.It Is A Good Daily Skin Care Product For You!

[Spot Treatment For All Skin Parts] Perfect For All Around Treatment Of Face And Body Acne. Directly Apply Lotion On The Affected Areas To Calm Tender Breakouts And Rinse Off In The Morning.Great As A Spot Treatment.

[Dry Out Blemishes & Pimple] Its Powerful Yet Gentle Formula Penetrates Deep Into Pores To Unclog Impurities, Reduce Redness, And Promote Clearer Skin. It Works Effectively To Dry Out Existing Blemishes While Preventing New Ones From Forming.

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#TOP 8

SIRUIMAO Premium Acne Spot Drying Lotion Kit

SIRUIMAO

7-10 days

SIRUIMAO Premium Acne Spot Drying Lotion Kit with Swab, Overnight Acne Treatment For Face, Dry Out Pimples, Blemishes, Zits And Clean Pores, 12ml / 0.41 FlOz

9.2

FTB Score

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Features

[TARGETS For Acne, Pimple And Blemish] - Apply This Before Bedtime And Let It Work Overnight. It's Designed To Target Whiteheads, Newly Formed Pimples, And Existing Acne. It Helps Diminish Acne And Keep Skin Smooth And Blemish-Free. We Provide 10Pcs Double-Head Swabs.

[FAST AND EFFECTIVE ACNE TREATMENT] - SIRUIMAO Acne Drying Lotion Kit Works Quickly To Reduce The Size And Severity Of Pimples And Blemishes. It Unblocks Clogged Pores By Dissolving Debris And Oil Buildup, Stopping The Root Cause Of Acne.

[TRUSTED FORMULA] - The Formula Is Specially Designed To Penetrate Pores And Provide Smooth, Blemish-Free Skin. It's Suitable For Dry To Oily Skin Types, Making It A Perfect Acne Treatment For Those With Delicate, Acne-Prone Skin.

[SUITABLE FOR ALL AGES] - This Drying Lotion Kit Can Be Used By Both Teens And Adults To Smooth Skin And Prevent Future Breakouts. It Targets Whiteheads, Acne, Blemishes, And Pimples On The Face, Back, Chest, Neck, And Other Acne-Prone Areas.

EASY TO USE] - This Is A 7-10 Day Treatment Course. After Receiving, Let The Pink Layer Settle To The Bottom. Use A Cotton Swab To Dip Into The Pink Layer And Apply Directly To Acne Area. Let It Dry Naturally - No Need To Rub. Avoid Using On Broken Skin, Lips, And Eyes. Keep Out Of Reach Of Children.

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#TOP 9

Acne Care Serum With Cotton Buds - Dark Spot Drying Lotion

Shengqialun

Acne Care Serum With Cotton Buds - Dark Spot Drying Lotion - Fast & Gentle Action For Acne Scar Removal，Blemish Control & Reduce Redness

9.1

FTB Score

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Features

[Dual-Layer ForRelief] The Unique Combination Of Water-Based And Powder-Based Layers In Our Spot Drying Lotion Works In Synergy. This Ensures Quick Absorption And Fast-Acting For Prompt Acne Care. It's The Ideal Spot Relief When You Need Immediate Relief From Those Unexpected Breakouts.

[Precise Acne Relief] Our Acne Relief Product Is Designed To Focus On Individual Pimples And Blemishes, Delivering Relief For Acne Control. Whether It's Pimple Cream-For Single Pimples, Or More Widespread Body Acne Needs.

[Daily Skincare Staple] Easily Fit This Dark Spot Cream And Dark Spot Remover For Face Into Your Daily Skincare Routine. It Offers Consistent Acne Care For Lasting Results, Making It An Essential Part Of Your Ongoing Acne Relief.

[All-Day Defense] Our Acne Serum Provides Continuous Protection Against Acne Throughout The Day. It Help To Gradually Fade Existing Acne Scars With Its Powerful Acne Scar Removal And Acne Scar Care Properties, Also Soothes Irritated Skin And Reduces Redness As Soon As It's Applied. It's Also Great For Tackling Back Blemish Care And Other Body Acne Concerns, Making It A Versatile Addition To Your Skincare Arsenal.

[Accelerated Pimple Ripening] This Product Speeds Up The Ripening Process Of Stubborn Pimples, While Calming And Soothing The Skin To Eliminate Redness. It Effectively Reduces The Discomfort And Visibility Of Breakouts, Acting As A Spot Cream For Those Troublesome Areas.

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#TOP 10

FREEDERM Fast Track Spot Treatment 25g

FREEDERM

100150

Clear

25 g (Pack of 1)

FREEDERM Fast Track Spot Treatment 25g Cover

FREEDERM Fast Track Visibly Reduces the Appearance of Individual Spots Within 3 Hours with Niacinamide, Clear, 25g

9.0

FTB Score

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The FREEDERM Fast Track is expertly designed for spot-prone skin, providing rapid relief by visibly reducing the appearance of individual spots within just three hours. Its formulation decreases both spot size and redness, helping you feel more confident in your skin. Enriched with niacinamide, a natural component of healthy skin, it promotes overall skin health. Enjoy the convenience of a fast application that delivers quick results, making it an ideal choice for those needing immediate care.

What We Like

Fast spot reduction

Decreases redness

Contains niacinamide

Quick application

Scientifically formulated

Frequently Asked Questions (FAQs)

1. What is the best treatment for spots on face?

Benzoyl peroxide It also helps to reduce the number of whiteheads and blackheads, and has an anti-inflammatory effect. Benzoyl peroxide is usually available as a cream or gel. It's used either once or twice a day. It should be applied 20 minutes after washing to all of the parts of your face affected by acne.

2. Can you use moisturizer as a spot treatment?

Don't consider moisturiser your enemy Choose a lightweight, non-comedogenic and gel-based formula that'll hydrate without aggravating your breakouts. In fact, if you're using a spot treatment, a moisturiser is a must.

Editor's Notes

During our lotion face spot treatment research, we found 38 lotion face spot treatment products and shortlisted 10 quality products. We collected and analyzed 16,618 customer reviews through our big data system to write the lotion face spot treatments list. We found that most customers choose lotion face spot treatments with an average price of £10.90.

The lotion face spot treatments are available for purchase. We have researched hundreds of brands and picked the top brands of lotion face spot treatments, including LANBENA, ISBEAUSOLS, Cureluxe, T-Zone, INSKIN.

Written by

Charlotte Powell

Charlotte Powell is a dermatologist and a licensed cosmetologist from Westminster, London. However, she was first a cosmetologist from London Beauty Training School. According to Charlotte, she needed better insight into the human skin, hence the dermatology degree. Long before she acquired her degree, she wrote and edited articles, eBooks, and editorials for companies and websites. Charlotte combines her skill and knowledge in providing DIY Beauty tips amongst other fashion related topics.