Best Multi Enzyme Supplements of 2025

Phoebe Cooper Avatar
Phoebe Cooper
Last Updated: 6 Feb 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Multi Enzyme Supplements are a type of dietary supplement that contain a blend of various enzymes that aid in the digestion and absorption of nutrients. These supplements may include enzymes such as amylase, lipase, protease, lactase and cellulase. They are designed to help break down carbohydrates, fats, proteins and lactose, and may be beneficial for individuals with digestive issues or those who want to improve their digestion and nutrient absorption. Multi Enzyme Supplements are widely available and can be found in various forms such as capsules, tablets, and powders.

At a Glance: Our Top Picks

Now Foods, Super Enzymes, 180 Capsules, Lab-Tested, Enzyme Blend, Gluten Free, Soy Free Cover #TOP 1
Now Foods, Super Enzymes, 180 Capsules, Lab-Tested, Enzyme Blend, Gluten Free, Soy Free
ftb score rating icon 9.8
BiOptimizers MassZymes | Digestive Enzyme Supplement for Better Absorption | Relief from Bloating, Constipation, and Gas for Men & Women | Contains Lipase, Amylase & Bromelain | 250 Capsules Cover #TOP 2
BiOptimizers MassZymes | Digestive Enzyme Supplement for Better Absorption | Relief from Bloating, Constipation, and Gas for Men & Women | Contains Lipase, Amylase & Bromelain | 250 Capsules
ftb score rating icon 9.7
Pure Encapsulations - Digestive Enzymes Ultra - Broad Spectrum Vegetarian Digestive Enzymes - 30 Capsules Cover #TOP 3
Pure Encapsulations - Digestive Enzymes Ultra - Broad Spectrum Vegetarian Digestive Enzymes - 30 Capsules
ftb score rating icon 9.5

Top 6 Multi Enzyme Supplements

#TOP 1

Now Foods, Super Enzymes, 180 Capsules, Lab-Tested, Enzyme Blend, Gluten Free, Soy Free

NOW
NOW-0591
Now Foods, Super Enzymes, 180 Capsules, Lab-Tested, Enzyme Blend, Gluten Free, Soy Free Cover
Now Foods, Super Enzymes, 180 Capsules, Lab-Tested, Enzyme Blend, Gluten Free, Soy Free

Features
GOOD BIOAVAILABILITY: Now Foods Super Enzymes Is Characterised By Good Bioavailability
HIGH-DOSAGE: One Dose, One Capsule, Of Super Enzymes By Now Foods Contains 200 Mg Of Betaine HCl And 100 Mg Of Ox Bile Extract That You Can Give To Your Body Every Day
WITHOUT UNWANTED ADDITIVES: Super Enzymes Capsules From Now Foods Are Gluten-Free And Made Without Genetic Engineering
IMPORTANT ENZYMES: Super Enzymes From Now Foods Contains 200 Mg Betaine HCl And 100 Mg Ox Gall Extract, Plus A Mixture Of Various Important Enzymes Such As Amylase, Protease And Lipase
HIGH QUALITY: Super Enzymes Capsules From Now Foods Are Tested In Independent Laboratories For Quality And Purity
#TOP 2

BiOptimizers MassZymes | Digestive Enzyme Supplement for Better Absorption | Relief from Bloating, Constipation, and Gas for Men & Women | Contains Lipase, Amylase & Bromelain | 250 Capsules

MZ250V4
Uncoloured
BiOptimizers MassZymes | Digestive Enzyme Supplement for Better Absorption | Relief from Bloating, Constipation, and Gas for Men & Women | Contains Lipase, Amylase & Bromelain | 250 Capsules Cover
BiOptimizers MassZymes | Digestive Enzyme Supplement for Better Absorption | Relief from Bloating, Constipation, and Gas for Men & Women | Contains Lipase, Amylase & Bromelain | 250 Capsules

Features
🫶 BOOST YOUR ENERGY: With 12 Powerful Digestive Enzymes Such As Protease, Amylase, Lipase, Lactase And Bromelain, You Can Have Better Gut Health And As A Result, May See A Lift In Your Energy, Focus, And Mood Levels
IMPROVE YOUR DIGESTION; MassZymes 4.0 Is A Digestive Enzyme Supplement That Contains Proteolytic Enzymes. This Supplement Can Help Provide Better Absorption Of Amino Acids That Feed Your Body, Therefore Helping Alleviate Constipation, Bloating, And Gas Relief
DIRECTIONS: Take 3 Capsules With Each Meal (May Take 1-3 Capsules With Each Meal And 1-2 Capsules Between Meals). Store In Cool And Dry Location
SUPPORT YOUR BODY: Full-Spectrum Digestive Enzymes Help Catalyze Numerous Reactions In Your Body. With Aging, The Reserves Of Our Digestive Enzymes Deplete, Leading To Nutrient Deficiencies, Fatigue, And Poor Skin Health. Fully Support Your System And Replenish Your Enzymes With Our Complete Formula
VEGAN FRIENDLY: This Digestive Supplement Is Derived From A Plant-Based Formulation That Does Not Contain Any Fillers Or Artificial Ingredients, Is Dairy-Free, Soy-Free, And Gluten-Free
#TOP 3

Pure Encapsulations - Digestive Enzymes Ultra - Broad Spectrum Vegetarian Digestive Enzymes - 30 Capsules

Pure Encapsulations - Digestive Enzymes Ultra - Broad Spectrum Vegetarian Digestive Enzymes - 30 Capsules Cover
Pure Encapsulations - Digestive Enzymes Ultra - Broad Spectrum Vegetarian Digestive Enzymes - 30 Capsules

Features
Digestive Support: Intake Of Pure Encapsulations Digestive Enzymes Ultra Contributes To Breakdown Of Dietary Fats And Fatty Foods
Active Ingredients: Provides A High-Strength, Broad-Spectrum Vegetarian Digestive Enzymes Involved In The Digestion Of Protein, Carbohydrate, Fat, Fiber And Lactose. The Recommended Dosage Of This Digestive Enzymes Ultra Supplement Is 2 Capsules With Each Meal, Or As Directed By A Health Professional
Pure Quality: Our Digestive Enzymes Ultra Pure Are Made With Only Premium Ingredients Sourced From Trusted Suppliers And Guided By Our Nutritional Experts, Then Carefully Manufactured And Tested To Verify Their Potency And Purity.
Pure Difference: All Pure Encapsulations Products Are FREE FROM Wheat, Eggs, Tree Nuts & Peanuts, Gluten, Artificial Colours, Flavours & Sweeteners, Coatings And Shellacs, GMOs, Unnecessary Binders, Fillers & Preservatives
45 Days Of Supply: Aside From Just A High Strength Of Enzymes / Digestive, This Supplement Also Assists With The Digestion Of Carbohydrates And Fibres, As Well As Dairy Products
#TOP 4

Fitness Health Bacillus Coagulans CFU 120 Tablets 500MG | Vegan Multi-Strain Live Digestive Enzyme Supplement for Men & Women | Help in Immune Support & Better Gut Health

S_ BACCOA-TB_0
Fitness Health Bacillus Coagulans CFU 120 Tablets 500MG | Vegan Multi-Strain Live Digestive Enzyme Supplement for Men & Women | Help in Immune Support & Better Gut Health Cover
Fitness Health Bacillus Coagulans CFU 120 Tablets 500MG | Vegan Multi-Strain Live Digestive Enzyme Supplement for Men & Women | Help in Immune Support & Better Gut Health

Features
FIGHTS HARMFUL MICROORGANISMS: Probiotics Are Live Microorganisms That Are Intended To Have Health Benefits When Consumed Or Applied To The Body. Probiotics Are Often Called "good" Or "helpful" Microorganisms Because They Help Keep Your Gut Healthy. Our Bacillus Coagulans CFU Tablets Hold Back The Growth Of Harmful Microorganisms And Are Great To Get To Bring Calm In An Extreme Gut Environment.
MULTIPLE HEALTH BENEFITS: Did You Know Your Gut Is Home To 70% Of Your Immune System? Bacillus Coagulans Is A Type Of Microorganism. It Is Used Similarly To Lactobacillus And Other Probiotics As "beneficial" Microorganisms.
FITNESS HEALTH UK MADE TRUSTED BRAND: Many Supplements Have Been Imported From Other Countries And Often Simply Bottled Here In The UK. Our Products Are 100% Manufactured In The UK And Are GMP Compliant. Laboratory Examination, Trusted Ingredients, Superior Quality. Non-GMO, Gluten Free, NO Artificial Flavors. Made And Processed Within The UK, Contains All Components Consumable For Vegans Men, And Women.
CONVENIENT RECYCLABLE PACKING: We Are Reducing Our Amount Of Plastic Usage And Using Products, Which Are Better For The Planet. We Are Using A Bag That Is Made With An Additive And Polymer Made From Cornstarch Allowing The Same Strong And Weatherproof Performance As Plastic But Without The Negative Impact.
ACTIVE INGREDIENTS: Fitness Health Bacillus Coagulans CFU Tablets Contain Bacillus Coagulans Sporebiotic 33.33mg (ex. Lactobacillus Sporogenes) 15 Billion/g Vegan Cellulose, Bacillus Coagulans, Magnesium Stearate. Take One Tablet Per Day With Water. Do Not Exceed The Stated Dose.
#TOP 5

DAOkids - Dietary Management of DAO Deficiency/Histamine Intolerance - DAO Enzyme for Children Aged 3 Years and Older - 60 Mini Gastro-Resistant Tablets

8437009482957
DAOkids - Dietary Management of DAO Deficiency/Histamine Intolerance - DAO Enzyme for Children Aged 3 Years and Older - 60 Mini Gastro-Resistant Tablets Cover
DAOkids - Dietary Management of DAO Deficiency/Histamine Intolerance - DAO Enzyme for Children Aged 3 Years and Older - 60 Mini Gastro-Resistant Tablets.

Features
CONTAINS Diamine Oxidase (DAO) Enzyme With High Metabolic Activity And Bioavailability.
BASED On Scientific And Clinical Evidence. More Information At Dr-Healthcare.com
GASTRORESISTANT COATED MINI TABLETS For The Controlled Release Of Active Ingredients At Their Sites And Times Of Peak Activity.
For The Dietary Management Of Neurological, Dermatological, Gastrointestinal And Muscular Symptoms Caused By DAO Deficiency / Histamine Intolerance In Children From 3 Years Old
FSMP (Food For Special Medical Purposes) - RECOMMENDED By The International Society Of DAO Deficiency.
#TOP 6

Fairvital | Multi Vegi Enzyme - 100% Plant-Based Enzyme Complex with bromelain + Papain + amylase + lipase + protease + Rutin - 90 Capsules (DRcaps™)

65009
Fairvital | Multi Vegi Enzyme - 100% Plant-Based Enzyme Complex with bromelain + Papain + amylase + lipase + protease + Rutin - 90 Capsules (DRcaps™) Cover
Fairvital | Multi Vegi Enzyme - 100% Plant-Based Enzyme Complex with bromelain + Papain + amylase + lipase + protease + Rutin - 90 Capsules (DRcaps™)

Features
WITHOUT: Gluten, Lactose, Fructose, Magnesium Stearate, Preservatives, Soy, Yeast, Pesticides, Fungicides, Artificial Fertilisers, Colourings, Stabilisers And Genetic Engineering (NON-GMO).
Fairvital GERMAN QUALITY: Daily Dosage: 3 Capsules Per Day Contain 360mg Bromelain, 360mg Papain, 300mg Amylase, 150mg Lipase, 150mg Protease And 180mg Rutin. High Dosage! Excellent Value For Money!
MICROBIAL PURITY: We Produce According To HACCP Quality Assurance And Use High-Quality Raw Materials. All Raw Materials Are Analysed For Pesticides And Heavy Metals Before Production. Fairvital Stands For Over 10 Years For Health, Innovation And Trust. Made In Germany: Ingredients From EU And Non-EU Countries.
1-MONTH SUPPLY: Long Shelf Life In Airtight Sealed Can. 90 Enzyme Capsules - More Efficiency Than Powder And Liquid! In A Light Can With A Practical Dosage Lid!
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is a multi enzyme supplement?

This medication contains digestive enzymes, which are natural substances needed by the body to help break down and digest food. It is used when the pancreas cannot make or does not release enough digestive enzymes into the gut to digest the food.

2. What are the benefits of multi enzymes?

They might claim to:. support healthy digestion.optimize the breakdown of fats, carbohydrates, and protein.promote optimal nutrient absorption.reduce gas, bloating, indigestion, and constipation following meals.help your body process difficult-to-digest foods.support colon health.

3. Are supplemental digestive enzymes good for you?

“Overall, a healthy person really doesn't need to take digestive enzyme supplements,” Denhard explains. “The best digestive enzymes are the ones our bodies make naturally, and they work best when you eat a whole food diet.”

4. What are enzymes vitamins good for?

Digestive enzymes are essential to nutrition and overall good health. They help your body absorb nutrients from the foods you eat. Without them, certain foods can lead to uncomfortable symptoms, food intolerances, or nutritional deficiencies.

Editor's Notes

During our multi enzyme supplement research, we found 7 multi enzyme supplement products and shortlisted 6 quality products. We collected and analyzed 11,627 customer reviews through our big data system to write the multi enzyme supplements list. We found that most customers choose multi enzyme supplements with an average price of £30.28.

The multi enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of multi enzyme supplements, including NOW, BiOptimizers, Pure Encapsulations, Fitness Health, DR Healthcare. The seller of top 1 product has received honest feedback from 626 consumers with an average rating of 4.9.

Written by
Phoebe Cooper Avatar

In 2000, Phoebe Cooper graduated from the University of London as a Pharmacist. She practiced as a Pharmacist for the better part of 2 decades. Phoebe says she has worked in the majority of health sectors and has sufficient accumulated knowledge and experience. In her practice, Phoebe published a series of eBooks, one of which is titled "Good Health Good Living."