Best Immune Support Vitamin B12 Supplements of 2026

Phoebe Cooper Avatar
Phoebe Cooper
Last Updated: 6 Feb 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

These vitamin B12 supplements are designed to provide immune system support. They contain a high dose of vitamin B12, which is essential for the proper functioning of the immune system. These supplements are suitable for individuals who have a vitamin B12 deficiency or those who want to boost their immune system. The supplements are easy to take and come in a convenient capsule form. They are recommended by health experts and have received positive reviews from satisfied customers.

At a Glance: Our Top Picks

High Strength Vegan B12 Tablets 1000mcg Cover #TOP 1
High Strength Vegan B12 Tablets 1000mcg
ftb score rating icon 9.8
YouNutri Vegan Vitamin B12 Tablets - 1000mcg Cover #TOP 2
YouNutri Vegan Vitamin B12 Tablets - 1000mcg
ftb score rating icon 9.7
Nutroliq B12 Liquid Drops for Energy and Focus Cover #TOP 3
Nutroliq B12 Liquid Drops for Energy and Focus
ftb score rating icon 9.5

Top 5 Immune Support Vitamin B12 Supplements

High Strength Vegan B12 Tablets 1000mcg

High Strength Vegan B12 Tablets 1000mcg Cover
Vitamin B12 High Strength Tablets - 1000mcg Vegan B12 Vitamin Methylcobalamin Supplement – Contributes to The Reduction of Tiredness and Fatigue & Immune Energy Support Made in the UK (4 Month Supply)

New Leaf B12 Tablets provide a high strength dose of 1000mcg of Vitamin B12 in a small, easy-to-swallow tablet. This essential vitamin plays a key role in converting food into energy, which can help reduce feelings of tiredness and fatigue. As a vegan-friendly option, these tablets ensure you receive vital B12 without animal products. They are produced under stringent safety and quality standards, giving you peace of mind about what you’re consuming.

What We Like
High strength dosage
Easy to swallow
Supports energy levels
Vegan-friendly
Stringent quality testing
#TOP 2

YouNutri Vegan Vitamin B12 Tablets - 1000mcg

YouNutri
YouNutri Vegan Vitamin B12 Tablets - 1000mcg Cover
Vitamin B12 Tablets High Strength – 450 Tablets (14+ Months Supply) 1000mcg Vegan B12 Supplement Pure Methylcobalamin – Energy and Immune Support – GMP Approved and Lab Tested

YouNutri B12 Tablets offer a high potency of 1000μg methylcobalamin, promoting optimal absorption to help boost your energy levels and reduce fatigue. With a supply for over 14 months, you only need to take one tablet a day, ensuring convenience and value. The tiny 5mm tablets are easy to swallow and digest, making them suitable for daily use. Scientifically proven to combat tiredness, these tablets support your overall health effectively.

What We Like
High potency for energy support
Long-lasting 14+ month supply
Easy to swallow tablets
Scientifically proven benefits

Nutroliq B12 Liquid Drops for Energy and Focus

Nutroliq Absorb Your Wellness Better
Nutroliq
60 ml (Pack of 1)
Nutroliq B12 Liquid Drops for Energy and Focus Cover
Nutroliq Vitamin B12 Liquid Drops - High-Strength 5000mcg Methylcobalamin Supplement - Energy Booster, Immune System Support, Better Concentration and Metabolism - Vegan & Vegetarian Formula - 60ml

Nutroliq B12 Drops provide an excellent way to boost your energy levels with 5000mcg of Methylcobalamin, the most absorbable form of vitamin B12. This supplement helps combat fatigue, allowing you to feel more energetic throughout your day. Additionally, it supports nervous system health by aiding in the regeneration of nerve fibre sheaths, which is crucial for effective nerve transmission. Regular use can also improve your mood and concentration, making it easier for you to stay focused and positive.

What We Like
High absorption of vitamin B12
Boosts energy and reduces fatigue
Supports nervous system health
Improves mood and concentration
Easy to take liquid form
#TOP 4

Viridian High Potency Vitamin B12 1000μg

Viridian High Potency Vitamin B12 1000μg Cover
Viridian - Vitamin B12 1000μg, High Potency - 60 Caps | Two Active Forms of B12 | Normal Red Blood Cell Formation, Immune Support | Reduce Tiredness & Fatigue | Nutritionist Formulated

The Viridian Vitamin B12 offers a high-strength formulation with 1000μg of active B12 in two essential forms, supporting your energy production and red blood cell formation. This supplement is particularly beneficial if you experience tiredness or fatigue, helping you maintain your energy levels throughout the day. Additionally, it supports your immune function, contributing to a healthy immune response and overall wellness. Being vegan-friendly, it ensures a clean and responsible choice for your health.

What We Like
High potency formula
Reduces tiredness and fatigue
Supports immune function
Vegan-friendly
Ethically formulated

Healthspan Vitamin B12 Tablets for Energy

VB12T240-AMAZON
Healthspan Vitamin B12 Tablets for Energy Cover
Healthspan Vitamin B12 1,000µg | 240 Tablets | Immune Support | Tiredness & Fatigue | One-A-Day Tablet | Easy to Swallow | Vegan

Healthspan B12 Tablets provide essential Vitamin B12, crucial for forming red blood cells that transport oxygen and nutrients throughout your body. This supplement uses methylcobalamin, a natural form of Vitamin B12, making it easier for you to swallow. Quality is paramount, as Healthspan sources the finest ingredients to ensure optimal purity and effectiveness. With 25 years of experience, they collaborate with experts to create innovative nutritional solutions, helping you maintain your immune health and energy levels effectively.

What We Like
Easy to swallow
High-quality ingredients
Natural methylcobalamin form
Supports immune health
Promotes energy levels
Buying Guide Image
Editor's Notes

During our immune support vitamin b12 supplement research, we found 104 immune support vitamin b12 supplement products and shortlisted 5 quality products. We collected and analyzed 14,616 customer reviews through our big data system to write the immune support vitamin b12 supplements list. We found that most customers choose immune support vitamin b12 supplements with an average price of £7.05.

The immune support vitamin b12 supplements are available for purchase. We have researched hundreds of brands and picked the top brands of immune support vitamin b12 supplements, including NEW LEAF PRODUCTS, YouNutri, Nutroliq Absorb Your Wellness Better, Viridian, healthspan.

Written by
Phoebe Cooper Avatar

In 2000, Phoebe Cooper graduated from the University of London as a Pharmacist. She practiced as a Pharmacist for the better part of 2 decades. Phoebe says she has worked in the majority of health sectors and has sufficient accumulated knowledge and experience. In her practice, Phoebe published a series of eBooks, one of which is titled "Good Health Good Living."