Best O'Keeffe's Hand Creams of 2026

Charlotte Powell Avatar
Charlotte Powell
Last Updated: 2 Feb 2026

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O'Keeffe's Hand Creams are a range of highly effective moisturisers designed to soothe and protect dry, cracked skin. These creams are formulated with a unique blend of ingredients that help to hydrate and nourish the skin, leaving it feeling soft and supple. With a range of different products to choose from, including fragrance-free and non-greasy options, there is an O'Keeffe's Hand Cream to suit every need. Whether you suffer from dry skin due to harsh weather conditions or frequent hand washing, O'Keeffe's Hand Creams are sure to provide relief and leave your hands feeling silky smooth.

At a Glance: Our Top Picks

O'Keeffe's Working Hands Hand Cream for Dry Skin Cover #TOP 1
O'Keeffe's Working Hands Hand Cream for Dry Skin
ftb score rating icon 9.8
O’Keeffe’s Working Hands Hand Cream for Dry Skin Cover #TOP 2
O’Keeffe’s Working Hands Hand Cream for Dry Skin
ftb score rating icon 9.7
O'Keeffe's Working Hands Hydrating Hand Cream 193g Cover #TOP 3
O'Keeffe's Working Hands Hydrating Hand Cream 193g
ftb score rating icon 9.5

Top 10 O'Keeffe's Hand Creams

O'Keeffe's Working Hands Hand Cream for Dry Skin

K0290001
Green
80 ml (Pack of 1)
O'Keeffe's Working Hands Hand Cream for Dry Skin Cover
O'Keeffe's Working Hands, 80ml Tube - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O'Keeffe's Working Hands is a powerful hand cream designed specifically for extremely dry and cracked skin. Its concentrated formula provides long-lasting hydration, making it ideal for those who often suffer from dryness. The cream contains Glycerin, which helps to lock moisture into your skin, creating a protective barrier that prevents further moisture loss. Best of all, this non-greasy formula ensures that you can use it throughout the day without leaving a sticky residue, allowing you to keep your hands in top condition.

What We Like
Highly concentrated for effective hydration
Creates a protective moisture barrier
Non-greasy formula for all-day use
Contains Glycerin for added moisture

O’Keeffe’s Working Hands Hand Cream for Dry Skin

112485
Multi-Colour
96 g (Pack of 1)
O’Keeffe’s Working Hands Hand Cream for Dry Skin Cover
O’Keeffe’s Working Hands, 96g Jar - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O’Keeffe’s Working Hands is a highly concentrated hand cream designed to hydrate and relieve extremely dry and cracked skin. It works by creating a protective barrier that locks in moisture, ensuring your hands remain well-hydrated. With Glycerin as one of the key ingredients, this cream effectively retains moisture in the skin, providing long-lasting relief. The non-greasy formula allows you to apply it at any time without leaving a sticky residue, making it perfect for all-day use.

What We Like
Deeply hydrates dry skin
Forms a protective barrier
Non-greasy and easy to apply
Long-lasting moisturisation
#TOP 3

O'Keeffe's Working Hands Hydrating Hand Cream 193g

112329
Green
193 g (Pack of 1)
O'Keeffe's Working Hands Hydrating Hand Cream 193g Cover
O'Keeffe's® Working Hands Value Size Jar 193g, packaging may vary

The O'Keeffe's Working Hands is a highly concentrated hand cream designed to deeply hydrate and relieve even the driest, cracked skin. It works by creating a protective barrier on your skin's surface, which helps lock in moisture and keeps your hands hydrated for longer. With ingredients like glycerin, it effectively seals in moisture, providing lasting comfort. Plus, its non-greasy formula means it absorbs quickly without leaving a sticky residue, so you can go about your day feeling comfortable and cared for.

What We Like
Highly concentrated hydration
Protective moisture barrier
Contains glycerin for locking moisture
Non-greasy formula
#TOP 4

O'Keeffe's Working Hands Eczema Relief Cream

AO-I2K9-ORS1
57 g (Pack of 1)
O'Keeffe's Working Hands Eczema Relief Cream Cover
O'Keeffe's Working Hands Eczema Relief Hand Cream, 57g - For Extremely Dry, Itchy, Irritated Hands | Steroid Free, Dermatologically Tested with 48-hour itch relief in 1 use

O'Keeffe's Eczema Relief is designed to treat dry skin conditions like eczema, helping to soothe itching, redness, scaling, and dryness. Its clinically tested formula includes colloidal oatmeal, which locks in moisture and aids skin repair, giving you softer, healthier hands. The cream is steroid free, making it safe for daily use and convenient to apply whenever needed. You will also benefit from its impressive 48-hour itch relief after just one application, leaving your skin hydrated, comfortable, and visibly improved.

What We Like
Treats eczema symptoms effectively
Contains skin-repairing oatmeal
Steroid free and safe daily use
Provides 48-hour itch relief
#TOP 5

O'Keeffe's Working Hands Hand Cream for Dry Skin

O'Keeffe's - K0350007 - 2pk #2
White
96 g (Pack of 2)
O'Keeffe's Working Hands Hand Cream for Dry Skin Cover
O'Keeffe's Working Hands, 96g Jar (2 Pack) - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O'Keeffe's Working Hands is a highly concentrated hand cream designed to hydrate and soothe extremely dry, cracked hands. It works by creating a protective barrier on your skin, which helps lock in moisture and prevents it from escaping, so your hands stay moisturised for longer. The formula includes glycerin, a powerful ingredient that keeps your skin hydrated and protected. Best of all, it is non-greasy, making it comfortable to use throughout the day and night without any sticky residue.

What We Like
Highly concentrated formula
Protects and locks in moisture
Contains glycerin for hydration
Non-greasy and fast absorbing
#TOP 6

O’Keeffe’s Working Hands Pumpable Hand Cream 260ml

260 ml (Pack of 1)
O’Keeffe’s Working Hands Pumpable Hand Cream 260ml Cover
O’Keeffe’s Working Hands Hand Cream 260ml – Pumpable Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O’Keeffe’s Working Hands is a highly concentrated hand cream designed to provide intense hydration and relief for extremely dry, cracked hands. Its pumpable formula makes application easy and mess-free, so you only need a small amount each time. The cream works by creating a protective barrier on your skin, locking in moisture to prevent further dryness and damage. Enriched with glycerin, it ensures your hands stay moisturised and protected throughout the day, helping you maintain healthy skin even in tough conditions.

What We Like
Highly concentrated for deep hydration
Easy pump application
Creates protective moisture barrier
Contains glycerin to lock moisture
#TOP 7

O'Keeffe's Working Hands Overnight 80ml Twin Pack

7144204
cream
80 g (Pack of 2)
O'Keeffe's Working Hands Overnight 80ml Twin Pack Cover
O'Keeffe's Working Hands Overnight 80ml & Working Hands 80ml (Twin Pack - Hands)

O'Keeffe's Working Hands offers visible results in just one night, making it a perfect choice for anyone struggling with dry skin. This highly-concentrated hand cream hydrates and relieves dryness, ensuring long-lasting moisturisation even for severely cracked hands. You will appreciate how the deep conditioning oils can smooth and soften your skin, providing intense hydration as you sleep. Plus, its non-greasy formula means it won't interfere with your daily activities, allowing you to enjoy its benefits without any fuss.

What We Like
Visible results overnight
Highly concentrated formula
Deeply hydrates and relieves
Non-greasy application
#TOP 8

O'Keeffe's Working Hands Overnight Cream

O'Keeffe's - K3200502
cream
85 g (Pack of 1)
O'Keeffe's Working Hands Overnight Cream Cover
O'Keeffe's Working Hands Overnight 80ml

O'Keeffe's Overnight Cream is designed to deliver visible results in just one night. You can wake up to noticeably softer and smoother skin, thanks to its intensive moisturisation. This cream deeply conditions your hands, providing the hydration needed to relieve and repair dry skin. Clinically proven, it ensures effective results, making it a reliable choice for those seeking overnight relief for their hands.

What We Like
Visible results overnight
Intensive moisturisation
Softens and smoothes skin
Clinically proven effectiveness
#TOP 9

O'Keeffe's Working Hands Hand Cream for Dry Skin

K0350002-6
Nylon/A
96 g (Pack of 6)
O'Keeffe's Working Hands Hand Cream for Dry Skin Cover
O'Keeffe's Working Hands, 96g Jar (6 Pack) - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O'Keeffe's Working Hands is a highly concentrated hand cream designed to hydrate and relieve even the most severe dry and cracked skin. It works by creating a protective barrier that locks in moisture, helping to restore your skin’s natural defences. The cream contains glycerin, an ingredient that effectively retains moisture and supports skin protection. Despite its intense hydration, the formula is non-greasy, so it absorbs quickly and feels comfortable to wear all day and night. Using O'Keeffe's Working Hands means your hands stay moisturised and protected while you carry on with your daily tasks.

What We Like
Highly concentrated moisturiser
Creates protective moisture barrier
Contains glycerin for hydration
Non-greasy formula
#TOP 10

O'Keeffe's Working Hands & Healthy Feet Pack

9044800
cream
93.5 ml (Pack of 2)
O'Keeffe's Working Hands & Healthy Feet Pack Cover
O'Keeffe's Working Hands 96g & Healthy Feet 91g (Twin Pack)

O'Keeffe's Hand & Foot Cream is a powerful solution for dry skin on hands and feet. Its hardworking formula delivers intense hydration, ensuring that even the most severe cases of dryness are effectively treated. You will appreciate how quickly it absorbs into the skin, drawing moisture right where it’s needed. Additionally, it forms a protective layer on the skin's surface, which helps to prevent further moisture loss and seals in hydration for lasting comfort. Say goodbye to cracked skin with this essential cream.

What We Like
Effective for severe dryness
Quickly absorbs into skin
Forms protective moisture layer
Long-lasting hydration
Buying Guide Image
Editor's Notes

During our O'Keeffe's hand cream research, we found 17 O'Keeffe's hand cream products and shortlisted 10 quality products. We collected and analyzed 743,093 customer reviews through our big data system to write the O'Keeffe's hand creams list. We found that most customers choose O'Keeffe's hand creams with an average price of £13.03.

The O'Keeffe's hand creams are available for purchase. The top 10 picks range in price from a low of £5.00 to a high of £36.00, find the one that fits your budget.

Written by
Charlotte Powell Avatar

Charlotte Powell is a dermatologist and a licensed cosmetologist from Westminster, London. However, she was first a cosmetologist from London Beauty Training School. According to Charlotte, she needed better insight into the human skin, hence the dermatology degree. Long before she acquired her degree, she wrote and edited articles, eBooks, and editorials for companies and websites. Charlotte combines her skill and knowledge in providing DIY Beauty tips amongst other fashion related topics.