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Best O'Keeffe's Hand Creams of 2026

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Charlotte Powell

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O'Keeffe's Hand Creams are a range of highly effective moisturisers designed to soothe and protect dry, cracked skin. These creams are formulated with a unique blend of ingredients that help to hydrate and nourish the skin, leaving it feeling soft and supple. With a range of different products to choose from, including fragrance-free and non-greasy options, there is an O'Keeffe's Hand Cream to suit every need. Whether you suffer from dry skin due to harsh weather conditions or frequent hand washing, O'Keeffe's Hand Creams are sure to provide relief and leave your hands feeling silky smooth.

At a Glance: Our Top Picks

Top 10 O'Keeffe's Hand Creams

O'Keeffe's Working Hands Hand Cream for Dry Skin

O'Keeffe's Working Hands Hand Cream for Dry Skin Cover

O'Keeffe's Working Hands, 80ml Tube - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O'Keeffe's Working Hands is a powerful hand cream designed specifically for extremely dry and cracked skin. Its concentrated formula provides long-lasting hydration, making it ideal for those who often suffer from dryness. The cream contains Glycerin, which helps to lock moisture into your skin, creating a protective barrier that prevents further moisture loss. Best of all, this non-greasy formula ensures that you can use it throughout the day without leaving a sticky residue, allowing you to keep your hands in top condition.

9.8
FTB Score

What We Like

  • Highly concentrated for effective hydration
  • Creates a protective moisture barrier
  • Non-greasy formula for all-day use
  • Contains Glycerin for added moisture

O’Keeffe’s Working Hands Hand Cream for Dry Skin

O’Keeffe’s Working Hands Hand Cream for Dry Skin Cover

O’Keeffe’s Working Hands, 96g Jar - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O’Keeffe’s Working Hands is a highly concentrated hand cream designed to hydrate and relieve extremely dry and cracked skin. It works by creating a protective barrier that locks in moisture, ensuring your hands remain well-hydrated. With Glycerin as one of the key ingredients, this cream effectively retains moisture in the skin, providing long-lasting relief. The non-greasy formula allows you to apply it at any time without leaving a sticky residue, making it perfect for all-day use.

9.7
FTB Score

What We Like

  • Deeply hydrates dry skin
  • Forms a protective barrier
  • Non-greasy and easy to apply
  • Long-lasting moisturisation
#TOP 3

O'Keeffe's Working Hands Hydrating Hand Cream 193g

O'Keeffe's Working Hands Hydrating Hand Cream 193g Cover

O'Keeffe's® Working Hands Value Size Jar 193g, packaging may vary

The O'Keeffe's Working Hands is a highly concentrated hand cream designed to deeply hydrate and relieve even the driest, cracked skin. It works by creating a protective barrier on your skin's surface, which helps lock in moisture and keeps your hands hydrated for longer. With ingredients like glycerin, it effectively seals in moisture, providing lasting comfort. Plus, its non-greasy formula means it absorbs quickly without leaving a sticky residue, so you can go about your day feeling comfortable and cared for.

9.5
FTB Score

What We Like

  • Highly concentrated hydration
  • Protective moisture barrier
  • Contains glycerin for locking moisture
  • Non-greasy formula
#TOP 4

O'Keeffe's Working Hands Eczema Relief Cream

O'Keeffe's Working Hands Eczema Relief Cream Cover

O'Keeffe's Working Hands Eczema Relief Hand Cream, 57g - For Extremely Dry, Itchy, Irritated Hands | Steroid Free, Dermatologically Tested with 48-hour itch relief in 1 use

O'Keeffe's Eczema Relief is designed to treat dry skin conditions like eczema, helping to soothe itching, redness, scaling, and dryness. Its clinically tested formula includes colloidal oatmeal, which locks in moisture and aids skin repair, giving you softer, healthier hands. The cream is steroid free, making it safe for daily use and convenient to apply whenever needed. You will also benefit from its impressive 48-hour itch relief after just one application, leaving your skin hydrated, comfortable, and visibly improved.

9.4
FTB Score

What We Like

  • Treats eczema symptoms effectively
  • Contains skin-repairing oatmeal
  • Steroid free and safe daily use
  • Provides 48-hour itch relief
#TOP 5

O'Keeffe's Working Hands Hand Cream for Dry Skin

  • O'Keeffe's
  • O'Keeffe's - K0350007 - 2pk #2
  • White
  • 96 g (Pack of 2)
O'Keeffe's Working Hands Hand Cream for Dry Skin Cover

O'Keeffe's Working Hands, 96g Jar (2 Pack) - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O'Keeffe's Working Hands is a highly concentrated hand cream designed to hydrate and soothe extremely dry, cracked hands. It works by creating a protective barrier on your skin, which helps lock in moisture and prevents it from escaping, so your hands stay moisturised for longer. The formula includes glycerin, a powerful ingredient that keeps your skin hydrated and protected. Best of all, it is non-greasy, making it comfortable to use throughout the day and night without any sticky residue.

9.3
FTB Score

What We Like

  • Highly concentrated formula
  • Protects and locks in moisture
  • Contains glycerin for hydration
  • Non-greasy and fast absorbing
#TOP 6

O’Keeffe’s Working Hands Pumpable Hand Cream 260ml

O’Keeffe’s Working Hands Pumpable Hand Cream 260ml Cover

O’Keeffe’s Working Hands Hand Cream 260ml – Pumpable Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O’Keeffe’s Working Hands is a highly concentrated hand cream designed to provide intense hydration and relief for extremely dry, cracked hands. Its pumpable formula makes application easy and mess-free, so you only need a small amount each time. The cream works by creating a protective barrier on your skin, locking in moisture to prevent further dryness and damage. Enriched with glycerin, it ensures your hands stay moisturised and protected throughout the day, helping you maintain healthy skin even in tough conditions.

9.1
FTB Score

What We Like

  • Highly concentrated for deep hydration
  • Easy pump application
  • Creates protective moisture barrier
  • Contains glycerin to lock moisture
#TOP 7

O'Keeffe's Working Hands Overnight 80ml Twin Pack

O'Keeffe's Working Hands Overnight 80ml Twin Pack Cover

O'Keeffe's Working Hands Overnight 80ml & Working Hands 80ml (Twin Pack - Hands)

O'Keeffe's Working Hands offers visible results in just one night, making it a perfect choice for anyone struggling with dry skin. This highly-concentrated hand cream hydrates and relieves dryness, ensuring long-lasting moisturisation even for severely cracked hands. You will appreciate how the deep conditioning oils can smooth and soften your skin, providing intense hydration as you sleep. Plus, its non-greasy formula means it won't interfere with your daily activities, allowing you to enjoy its benefits without any fuss.

8.9
FTB Score

What We Like

  • Visible results overnight
  • Highly concentrated formula
  • Deeply hydrates and relieves
  • Non-greasy application
#TOP 8

O'Keeffe's Working Hands Overnight Cream

  • O'Keeffe's
  • O'Keeffe's - K3200502
  • cream
  • 85 g (Pack of 1)
O'Keeffe's Working Hands Overnight Cream Cover

O'Keeffe's Working Hands Overnight 80ml

O'Keeffe's Overnight Cream is designed to deliver visible results in just one night. You can wake up to noticeably softer and smoother skin, thanks to its intensive moisturisation. This cream deeply conditions your hands, providing the hydration needed to relieve and repair dry skin. Clinically proven, it ensures effective results, making it a reliable choice for those seeking overnight relief for their hands.

8.7
FTB Score

What We Like

  • Visible results overnight
  • Intensive moisturisation
  • Softens and smoothes skin
  • Clinically proven effectiveness
#TOP 9

O'Keeffe's Working Hands Hand Cream for Dry Skin

O'Keeffe's Working Hands Hand Cream for Dry Skin Cover

O'Keeffe's Working Hands, 96g Jar (6 Pack) - Hand Cream for Extremely Dry, Cracked Hands | Instantly Boosts Moisture Levels, Creates a Protective Layer & Prevents Moisture Loss

O'Keeffe's Working Hands is a highly concentrated hand cream designed to hydrate and relieve even the most severe dry and cracked skin. It works by creating a protective barrier that locks in moisture, helping to restore your skin’s natural defences. The cream contains glycerin, an ingredient that effectively retains moisture and supports skin protection. Despite its intense hydration, the formula is non-greasy, so it absorbs quickly and feels comfortable to wear all day and night. Using O'Keeffe's Working Hands means your hands stay moisturised and protected while you carry on with your daily tasks.

8.5
FTB Score

What We Like

  • Highly concentrated moisturiser
  • Creates protective moisture barrier
  • Contains glycerin for hydration
  • Non-greasy formula
#TOP 10

O'Keeffe's Working Hands & Healthy Feet Pack

O'Keeffe's Working Hands & Healthy Feet Pack Cover

O'Keeffe's Working Hands 96g & Healthy Feet 91g (Twin Pack)

O'Keeffe's Hand & Foot Cream is a powerful solution for dry skin on hands and feet. Its hardworking formula delivers intense hydration, ensuring that even the most severe cases of dryness are effectively treated. You will appreciate how quickly it absorbs into the skin, drawing moisture right where it’s needed. Additionally, it forms a protective layer on the skin's surface, which helps to prevent further moisture loss and seals in hydration for lasting comfort. Say goodbye to cracked skin with this essential cream.

8.3
FTB Score

What We Like

  • Effective for severe dryness
  • Quickly absorbs into skin
  • Forms protective moisture layer
  • Long-lasting hydration

Editor's Notes

During our O'Keeffe's hand cream research, we found 17 O'Keeffe's hand cream products and shortlisted 10 quality products. We collected and analyzed 743,093 customer reviews through our big data system to write the O'Keeffe's hand creams list. We found that most customers choose O'Keeffe's hand creams with an average price of £13.03.

The O'Keeffe's hand creams are available for purchase. The top 10 picks range in price from a low of £5.00 to a high of £36.00, find the one that fits your budget.

Written by

Charlotte Powell Avatar

Charlotte Powell

Charlotte Powell is a dermatologist and a licensed cosmetologist from Westminster, London. However, she was first a cosmetologist from London Beauty Training School. According to Charlotte, she needed better insight into the human skin, hence the dermatology degree. Long before she acquired her degree, she wrote and edited articles, eBooks, and editorials for companies and websites. Charlotte combines her skill and knowledge in providing DIY Beauty tips amongst other fashion related topics.