Best Lice Shampoos & Rinses of 2025

Phoebe Cooper Avatar
Phoebe Cooper
Last Updated: 2 Feb 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Lice shampoos and rinses are specially formulated products designed to effectively eliminate head lice and their eggs. These products are typically used as a part of a comprehensive lice treatment plan, which may also include the use of a lice comb, washing and drying of bedding and clothing, and cleaning of household surfaces. Lice shampoos and rinses come in various formulations and strengths, and may be available over-the-counter or by prescription. They are a popular choice for parents and caregivers looking for a safe and effective way to get rid of head lice infestations.

At a Glance: Our Top Picks

NitNOT Headlice Treatment Serum for All Hair Cover #TOP 1
NitNOT Headlice Treatment Serum for All Hair
ftb score rating icon 9.9
Hedrin Head Lice Shampoo & Comb Kit Cover #TOP 2
Hedrin Head Lice Shampoo & Comb Kit
ftb score rating icon 9.8
Hedrin Once Liquid Gel for Lice Treatment Cover #TOP 3
Hedrin Once Liquid Gel for Lice Treatment
ftb score rating icon 9.6

Top 10 Lice Shampoos & Rinses

#TOP 1

NitNOT Headlice Treatment Serum for All Hair

Nitnot
N9-HW5M-69CN
Orange, White
200 ml (Pack of 1)
NitNOT Headlice Treatment Serum for All Hair Cover
NitNOT Headlice Treatment As Seen On Dragons Den100% Effective Kills All Head Lice and Eggs. Premium Nit Treatment Lotion(200ml). Lice Treatment Extra Defence for All Hair, for Children and Adults.

NitNOT Headlice Treatment is a highly effective solution for eliminating head lice and their eggs. This hypoallergenic serum is gentle on the scalp while targeting all life cycle stages of nits, ensuring complete eradication. Its UK professional grade eco formula is safe and odourless, making it suitable for the whole family. You will appreciate the easy application with the handy nozzle, allowing you to use only what you need, thus minimising waste and saving money.

What We Like
100% effective against lice
Hypoallergenic and safe for all
Easy application with no waste
Eco-friendly and vegan certified
#TOP 2

Hedrin Head Lice Shampoo & Comb Kit

4074373
Clear
2 Piece Set
Hedrin Head Lice Shampoo & Comb Kit Cover
Hedrin Head Lice Shampoo & Comb Kit, Kills Head Lice & Eggs in 5 Minutes, Clinically Tested, Suitable for Adults & Children, 100ml (4 x 25ml Treatments), (Formerly All-in-One - Packaging May Vary)

Hedrin Lice Shampoo Kit offers fast and effective relief from head lice and their eggs, eliminating them within just five minutes. This complete kit includes both shampoo and comb, providing you with a thorough lice treatment solution in one easy package. Clinically tested, it ensures safety and reliability for the entire family. With four 25ml treatments included, you have multiple applications available for ongoing lice management, making it convenient for any household facing infestations.

What We Like
Quick lice elimination
Includes comb for convenience
Clinically proven safety
Multiple treatments in one kit
Suitable for all ages
#TOP 3

Hedrin Once Liquid Gel for Lice Treatment

155558
Clear
250 ml (Pack of 1)
Hedrin Once Liquid Gel for Lice Treatment Cover
Hedrin Once Liquid Gel, Fast & Effective Lice & Nit Treatment, Kills Head Lice & Eggs, Clinically Tested, Suitable for Adults & Children, 1 x 250ml (10 x 25ml Treatments)

The Hedrin Once Gel is a fast and effective solution for eliminating head lice and their eggs. Its liquid gel formula makes application easy, ensuring that you can cover all areas thoroughly. Clinically tested, this product provides peace of mind with its proven safety and effectiveness. With a large 250ml bottle, you'll find great value, as it offers the equivalent of ten 25ml treatments, making it convenient for the whole family.

What We Like
Fast lice elimination
Easy-to-apply gel
Clinically tested for safety
Large size offers great value
Gentle on hair
#TOP 4

Lyclear Fast Action Head Lice Treatment

109557902
200 ml (Pack of 1)
Lyclear Fast Action Head Lice Treatment Cover
Lyclear Original Shampoo Head Lice Treatment + Head Lice Comb – Kills Head Lice and Washes Hair – Effective in Just 15 Minutes – 200 ml Shampoo Format and Nit Comb

Lyclear Head Lice Shampoo is designed for quick and effective treatment, working in just 15 minutes to eliminate head lice and their eggs. Its insecticide-free formula provides a gentle yet powerful solution, suffocating and dehydrating lice without harsh chemicals. You will appreciate the convenience of a product that not only treats lice but also washes your hair. Plus, the inclusion of an anti-head lice comb makes it easy to remove any remaining lice and eggs, ensuring peace of mind for you and your family.

What We Like
Fast-acting treatment
Insecticide-free formula
Comb included for easy use
Washes hair while treating
Multiple applications per bottle
#TOP 5

Hedrin Treat & Go Leave-In Spray for Lice

057118
Clear
60 ml (Pack of 1)
Hedrin Treat & Go Leave-In Spray for Lice Cover
Hedrin Treat & Go Leave-In Spray, Fast, No Fuss Lice & Nit Treatment, Kills Head Lice & Eggs, Clinically Tested, Suitable for Adults & Children, 1 x 60ml (2 x 30ml Treatments)

The Hedrin Treat & Go is a fast and easy-to-use leave-in spray, perfect for busy families dealing with lice. It quickly eliminates both head lice and their eggs, ensuring a thorough treatment. Clinically tested, this product is safe for all ages, giving you peace of mind. Its gentle formula is designed to be soft on hair, leaving it manageable while effectively combating lice without harsh chemicals.

What We Like
Fast and easy application
Kills lice and eggs
Safe for all ages
Gentle on hair
Two treatments in one pack
#TOP 6

Hedrin Treat & Go Leave-In Lotion for Lice

3630225
50 ml (Pack of 1)
Hedrin Treat & Go Leave-In Lotion for Lice Cover
Hedrin Treat & Go Leave-In Lotion, Fast, No Fuss Lice & Nit Treatment, Kills Head Lice & Eggs, Clinically Tested, Suitable for Adults & Children, 1 x 50ml (2 x 25ml Treatments)

Hedrin Leave-In Lotion offers a fast and fuss-free solution for treating head lice. This easy-to-use lotion works quickly, making it perfect for busy families. It effectively targets and eliminates both lice and their eggs, ensuring a thorough treatment. Clinically tested, it is proven safe for all ages, so you can use it with confidence on both adults and children. Plus, its gentle formula leaves hair soft and manageable, allowing you to tackle lice without harsh chemicals.

What We Like
Fast and easy application
Effective against lice and eggs
Clinically tested for safety
Suitable for all ages
Gentle on hair
#TOP 7

Lyclear Express Treat & Protect Shampoo

5000023524
200 ml (Pack of 1)
Lyclear Express Treat & Protect Shampoo Cover
Lyclear Express Treat & Protect Shampoo - Kills Head Lice & Eggs – Effective in Just 5 minutes on Head Lice - Helps Protect for up-to 72 Hours* & Washes Hair – Shampoo Format, 200ml

Lyclear Treat & Protect is a highly effective shampoo that tackles head lice in just 5 minutes. With its unique Lice Protection Factor technology, it provides up to 72 hours of protection, making your hair an unwelcoming place for lice and helping to prevent reinfestations. This gentle, insecticide-free formula is suitable for all hair types, effectively suffocating resistant "Super Lice". Plus, it rinses out easily, so you can wash your hair while treating it, leaving your locks soft and shiny.

What We Like
Fast-acting in 5 minutes
Up to 72 hours protection
Gentle on hair and skin
Easy to rinse out
Leaves hair soft and shiny
#TOP 8

Lyclear Express Lotion for Head Lice

5000023525
100 ml (Pack of 1)
Lyclear Express Lotion for Head Lice Cover
Lyclear Express Treat & Protect Lotion - Kills Head Lice & Eggs – Effective in Just 5 minutes on Head Lice & Helps Protect for up-to 72 hours* – 100ml Lotion Format

Lyclear Express Lotion offers a fast and effective solution for head lice, killing them in just 5 minutes. With its advanced Lice Protection Factor technology, it provides protection for up to 72 hours, helping to prevent reinfestations. The gentle, insecticide-free formula is safe for both hair and skin, making it suitable for all users. Additionally, it allows for easy rinsing and combing, ensuring you can effectively remove all eggs with thorough application.

What We Like
Fast action in 5 minutes
Protects for up to 72 hours
Gentle on hair and skin
Insecticide-free formula
Easy to rinse and comb
#TOP 9

Nitrid All-In-One Head Lice Treatment Spray

Nitrid
NHLT120ml
Nitrid All-In-One Head Lice Treatment Spray Cover
Nitrid All-In-One Head Lice Treatment Spray & Comb, 100% Effective, Kills Nits & Eggs, Includes Spray 120ml & Nit Comb

The Nitrid Lice Treatment Spray offers a comprehensive solution for eradicating head lice and their eggs. This clinically proven formula works effectively in just 10 minutes, allowing you to quickly address any infestations. With no skin irritation or unpleasant odours, it is a safe option for children. Additionally, the unique active ingredient, Dimethicone, ensures a gentle yet powerful treatment, making it a convenient choice for families dealing with lice.

What We Like
Clinically proven effectiveness
Fast results in 10 minutes
No skin irritation
Safe for children
#TOP 10

SB Body Wash for Lice and Mites

250 ml (Pack of 1)
SB Body Wash for Lice and Mites Cover
SB Body Wash 250ml Prevent & Clear Lice & Mites

SB Lice & Mites Wash offers a convenient solution for easing itching on the skin. By showering daily with this body wash, you can quickly alleviate discomfort caused by lice and mites. Just a few minutes each day will help you maintain cleanliness and comfort. This gentle, sulphate-free formula ensures your skin remains hydrated while promoting safety through blended enzymes. It's perfect for use at school, the gym, work, or even on holiday, making it easy for you to prevent and manage infestations.

What We Like
Effective against itching
Quick and easy to use
Gentle on all skin types
Sulphate-free formula
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can you wash lice out with regular shampoo?

Wash the hair with regular shampoo. Do not use a conditioner. It can keep the lice medicine from working. Rinse well with warm water and towel dry.

Editor's Notes

During our lice shampoos & rinse research, we found 56 lice shampoos & rinse products and shortlisted 10 quality products. We collected and analyzed 40,474 customer reviews through our big data system to write the lice shampoos & rinses list. We found that most customers choose lice shampoos & rinses with an average price of £11.29.

The lice shampoos & rinses are available for purchase. We have researched hundreds of brands and picked the top brands of lice shampoos & rinses, including Nitnot, Hedrin, Lyclear, Nitrid, TahoeBay. The seller of top 1 product has received honest feedback from 66 consumers with an average rating of 4.7.

Written by
Phoebe Cooper Avatar

In 2000, Phoebe Cooper graduated from the University of London as a Pharmacist. She practiced as a Pharmacist for the better part of 2 decades. Phoebe says she has worked in the majority of health sectors and has sufficient accumulated knowledge and experience. In her practice, Phoebe published a series of eBooks, one of which is titled "Good Health Good Living."