Best Antiseptic Foot Creams of 2025

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Antiseptic foot creams are specially formulated creams designed to soothe and protect the feet from various foot problems such as dryness, roughness, itching, and fungal infections. These creams are made with natural ingredients such as tea tree oil, eucalyptus oil, and lavender oil, which have antifungal, antiseptic, and antibacterial properties. They also contain moisturizing agents such as shea butter and glycerin to keep the feet soft and supple. Antiseptic foot creams are ideal for those who suffer from foot odor, athlete's foot, and other foot-related issues.
At a Glance: Our Top Picks
Top 10 Antiseptic Foot Creams
CCS Professional Foot Care Cream with Urea
The CCS Foot Care Cream is designed to effectively moisturise and protect your dry, callused feet. With its professional foot care formula, it prevents dry skin and cracked heels, ensuring your feet remain soft and smooth. The 10% urea content helps keep your skin supple, as it is a natural moisturiser found in the body. Additionally, this dermatologically tested cream is suitable for diabetics and those with sensitive skin, making it an ideal choice for anyone seeking gentle yet effective foot care.
O'Keeffe's Healthy Feet Cream for Dry Feet
O'Keeffe's Healthy Feet is a powerful foot cream designed to hydrate and relieve extremely dry, cracked feet. It works quickly to boost moisture levels, ensuring your feet feel soft and comfortable throughout the day. The cream also forms a protective layer that prevents further moisture loss, keeping your skin hydrated for longer. With its long-lasting effects, you can enjoy healthier feet that look and feel great, making it an essential addition to your skincare routine.
CCS Professional Foot Care Cream with Urea
The CCS Foot Care Cream is specially formulated to prevent dry skin and cracked heels, making it ideal for anyone seeking soft, smooth feet. With 10% urea, this cream helps maintain skin softness and suppleness, ensuring your feet feel comfortable all day. Its hypo-allergenic properties make it suitable for sensitive skin, so you can apply it with confidence. Additionally, the cream is dermatologically tested and safe for diabetics, allowing you to care for your feet without worry.
Rescue Foot Balm for Cracked Heels
CeraVe SA Renewing Foot Cream for Dry Skin
CeraVe Foot Cream is specifically designed for extremely dry, rough, and bumpy skin. Developed with dermatologists, it features three essential ceramides that help protect your skin's natural barrier, ensuring it stays healthy. The inclusion of salicylic acid allows the cream to exfoliate while moisturising, making it perfect for revitalising your feet. Additionally, its MVE technology locks in moisture, providing you with 24-hour hydration for soft and smooth feet. This non-greasy formula absorbs quickly, making it a convenient choice for daily use.
Tea Tree Foot Cream - Soothing Foot Cream
PediSalve Foot Cream Fast Relief Very Dry Feet Hard Skin. Cracked Heels Diabetic Foot Care. Shea butter Vit E. Developed by Medical Doctor Marble Hill 100g
O’Keeffe’s Healthy Feet Overnight Cream for Dry Feet
O’Keeffe’s Healthy Feet Cream is designed to deliver visible results overnight. As you sleep, this intensive foot cream works to relieve extremely dry, cracked feet. Its nourishing formula contains conditioning oils and shea butter, which soften rough skin and provide essential hydration. Clinically proven to be effective, this cream not only restores your skin but also gives you the comfort of knowing that relief is just a night's sleep away.
Frequently Asked Questions (FAQs)
1. What is a good antifungal foot cream?
Reviewed & Approved. Best Overall: Lotrimin AF Athlete's Foot Liquid Spray at Safeway.com.Best for Kids: Lotrimin AF Cream for Athlete's Foot at Amazon.Best Cream: Lamisil Athelete's Foot Antifungal Cream at Target.Best Foot Soak: Truremedy Naturals Tea Tree Oil Foot Soak at Amazon.Best Spray:
2. What is the cream for a sore foot?
Anti-fungal topical medications come in various forms such as cream, powder, or spray, and are used for treatment of athletes foot. Some common brand medicines are Lotrimin, Lamisil, and Desenex.
During our antiseptic foot cream research, we found 67 antiseptic foot cream products and shortlisted 10 quality products. We collected and analyzed 157,546 customer reviews through our big data system to write the antiseptic foot creams list. We found that most customers choose antiseptic foot creams with an average price of £7.57.
The antiseptic foot creams are available for purchase. We have researched hundreds of brands and picked the top brands of antiseptic foot creams, including CCS, O'Keeffe's, Daktarin, Botanicals, CeraVe.

Charlotte Powell is a dermatologist and a licensed cosmetologist from Westminster, London. However, she was first a cosmetologist from London Beauty Training School. According to Charlotte, she needed better insight into the human skin, hence the dermatology degree. Long before she acquired her degree, she wrote and edited articles, eBooks, and editorials for companies and websites. Charlotte combines her skill and knowledge in providing DIY Beauty tips amongst other fashion related topics.